Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv1083

Experiment: 7H9 with Isoniazid 0.025 ug/mL

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

Per-strain Table

Position	Strand	Gene	LocusTag	Fraction	7H9 with Isoniazid 0.025 ug/mL
1,206,466	-				-0.1
1,206,468	-				+0.2
1,206,478	-				+0.2
1,206,478	-				-1.0
1,206,478	-				-0.2
1,206,479	+				-1.0
1,206,789	-		Rv1082	0.31	-2.8
1,206,792	+		Rv1082	0.31	+0.4
1,206,793	-		Rv1082	0.31	-2.0
1,206,803	+		Rv1082	0.33	-0.7
1,206,910	+		Rv1082	0.45	-0.7
1,207,042	+		Rv1082	0.60	-0.4
1,207,042	+		Rv1082	0.60	-2.7
1,207,045	+		Rv1082	0.61	+0.2
1,207,046	-		Rv1082	0.61	+1.8
1,207,335	+				+1.0
1,207,648	-				+0.2
1,207,691	-				-0.5
1,207,710	+				+1.0
1,207,927	+		Rv1084	0.14	-0.3
1,207,928	-		Rv1084	0.14	+0.3
1,207,928	-		Rv1084	0.14	-0.4
1,208,021	-		Rv1084	0.19	-0.2
1,208,282	+		Rv1084	0.32	-0.3
1,208,294	-		Rv1084	0.33	-0.8
1,208,369	-		Rv1084	0.36	-0.9
1,208,369	-		Rv1084	0.36	-0.5
1,208,446	+		Rv1084	0.40	+0.4
1,208,630	-		Rv1084	0.49	-0.1
1,208,630	-		Rv1084	0.49	-0.4