Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv1076

Experiment: 7H9 with Isoniazid 0.025 ug/mL

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

Per-strain Table

Position	Strand	Gene	LocusTag	Fraction	7H9 with Isoniazid 0.025 ug/mL
1,199,868	-		Rv1075c	0.47	+0.3
1,199,919	-		Rv1075c	0.52	-1.1
1,199,919	-		Rv1075c	0.52	-0.2
1,200,210	+		Rv1075c	0.83	-0.9
1,200,210	+		Rv1075c	0.83	-0.5
1,200,210	+		Rv1075c	0.83	-0.6
1,200,211	-		Rv1075c	0.83	+0.4
1,200,212	+		Rv1075c	0.83	+0.6
1,200,212	+		Rv1075c	0.83	+0.9
1,200,254	+		Rv1075c	0.88	+0.6
1,200,306	+				+0.4
1,200,491	-				-0.3
1,200,608	-				-1.3
1,200,877	-		Rv1076	0.12	+0.5
1,200,877	-		Rv1076	0.12	+1.2
1,200,898	+		Rv1076	0.15	+1.1
1,200,898	+		Rv1076	0.15	+0.1
1,200,899	-		Rv1076	0.15	+0.4
1,200,899	-		Rv1076	0.15	+3.4
1,200,899	-		Rv1076	0.15	-0.0
1,200,899	-		Rv1076	0.15	+1.8
1,200,899	-		Rv1076	0.15	+2.6
1,201,152	-		Rv1076	0.43	+0.2
1,201,396	-		Rv1076	0.70	+0.2
1,201,485	+		Rv1076	0.80	-0.2
1,201,486	-		Rv1076	0.80	-0.7
1,201,486	-		Rv1076	0.80	+0.1
1,201,486	-		Rv1076	0.80	-0.1
1,201,637	+				-0.9
1,201,637	+				+1.0
1,201,638	-				+2.0
1,201,638	-				-0.8
1,201,734	+				+0.8
1,201,734	+				+1.6
1,201,734	+				+0.1
1,201,756	-				+1.2
1,201,823	-				+0.0
1,201,979	-		Rv1077	0.19	-0.7
1,202,041	+		Rv1077	0.23	+0.1
1,202,098	+		Rv1077	0.27	+0.7
1,202,099	-		Rv1077	0.27	-0.3
1,202,101	+		Rv1077	0.28	+1.8
1,202,101	+		Rv1077	0.28	-0.3
1,202,102	-		Rv1077	0.28	+0.0
1,202,130	+		Rv1077	0.30	-1.6
1,202,188	+		Rv1077	0.34	+1.8
1,202,188	+		Rv1077	0.34	+0.4
1,202,188	+		Rv1077	0.34	-0.3
1,202,189	-		Rv1077	0.34	+0.6
1,202,189	-		Rv1077	0.34	+0.1
1,202,318	+		Rv1077	0.43	+1.6
1,202,318	+		Rv1077	0.43	+0.1
1,202,319	-		Rv1077	0.43	+0.0
1,202,353	+		Rv1077	0.46	-0.2
1,202,378	-		Rv1077	0.47	+0.2
1,202,378	-		Rv1077	0.47	+1.3
1,202,419	+		Rv1077	0.50	+1.4
1,202,420	-		Rv1077	0.50	-1.4
1,202,617	+		Rv1077	0.65	-1.2
1,202,618	-		Rv1077	0.65	+0.6
1,202,618	-		Rv1077	0.65	+1.2