Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv1073

Experiment: 7H9 with Isoniazid 0.025 ug/mL

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

Per-strain Table

Position	Strand	Gene	LocusTag	Fraction	7H9 with Isoniazid 0.025 ug/mL
1,196,249	+				+0.8
1,196,301	+				-2.4
1,196,302	-				-1.7
1,196,302	-				-2.7
1,196,468	-		Rv1072	0.23	-1.1
1,196,674	+		Rv1072	0.47	-1.5
1,196,765	+		Rv1072	0.58	-0.2
1,197,071	+				-1.0
1,197,098	+				-1.4
1,197,099	-				-2.3
1,197,099	-				+0.1
1,197,099	-				-0.6
1,197,304	-				-0.2
1,197,304	-				+0.7
1,197,306	+				-1.5
1,197,306	+				+2.4
1,197,307	-				-0.2
1,197,371	+		Rv1073	0.16	+0.8
1,197,527	-		Rv1073	0.35	+0.4
1,197,527	-		Rv1073	0.35	+1.8
1,197,527	-		Rv1073	0.35	+0.4
1,197,572	+		Rv1073	0.40	+0.2
1,197,584	+		Rv1073	0.41	-0.4
1,197,584	+		Rv1073	0.41	+0.6
1,197,584	+		Rv1073	0.41	+1.4
1,197,584	+		Rv1073	0.41	-0.5
1,197,585	-		Rv1073	0.42	+0.5
1,197,585	-		Rv1073	0.42	+0.3
1,197,585	-		Rv1073	0.42	-1.0
1,197,585	-		Rv1073	0.42	-0.2
1,197,616	+		Rv1073	0.45	+1.8
1,197,616	+		Rv1073	0.45	+2.1
1,197,617	-		Rv1073	0.45	-0.7
1,197,680	+		Rv1073	0.53	-1.4
1,197,680	+		Rv1073	0.53	+0.4
1,197,727	+		Rv1073	0.58	+1.8
1,197,728	-		Rv1073	0.58	+0.3
1,197,728	-		Rv1073	0.58	+0.3
1,197,800	-		Rv1073	0.67	+0.5
1,197,864	+		Rv1073	0.74	+1.6
1,197,909	+		Rv1073	0.80	+0.1
1,197,909	+		Rv1073	0.80	+1.7
1,197,972	+		Rv1073	0.87	+0.6
1,197,973	-		Rv1073	0.87	+0.1
1,197,973	-		Rv1073	0.87	-0.2
1,198,235	+				+0.2
1,198,285	-		Rv1074c	0.11	-0.2
1,198,301	-		Rv1074c	0.12	-1.4
1,198,301	-		Rv1074c	0.12	+0.2
1,198,537	+		Rv1074c	0.31	+0.4
1,198,537	+		Rv1074c	0.31	+0.1
1,198,538	-		Rv1074c	0.31	-1.5
1,198,866	+		Rv1074c	0.58	+0.1
1,198,867	-		Rv1074c	0.58	+0.0
1,198,868	+		Rv1074c	0.58	-1.2
1,198,868	+		Rv1074c	0.58	-0.1
1,198,868	+		Rv1074c	0.58	-0.3
1,198,868	+		Rv1074c	0.58	-0.1
1,198,868	+		Rv1074c	0.58	-0.0
1,198,868	+		Rv1074c	0.58	-2.0
1,198,868	+		Rv1074c	0.58	+0.6
1,198,868	+		Rv1074c	0.58	+0.6
1,198,868	+		Rv1074c	0.58	-1.0
1,198,868	+		Rv1074c	0.58	-0.8
1,198,869	-		Rv1074c	0.59	+1.5
1,198,869	-		Rv1074c	0.59	+1.6
1,198,869	-		Rv1074c	0.59	+0.2
1,198,869	-		Rv1074c	0.59	+0.2
1,198,869	-		Rv1074c	0.59	+1.4
1,198,869	-		Rv1074c	0.59	-0.8
1,198,869	-		Rv1074c	0.59	+1.3
1,198,869	-		Rv1074c	0.59	-0.2
1,198,869	-		Rv1074c	0.59	+0.2
1,198,869	-		Rv1074c	0.59	+0.2
1,198,869	-		Rv1074c	0.59	+0.6
1,198,869	-		Rv1074c	0.59	+0.3