Experiment: 7H9 with Isoniazid 0.025 ug/mL
Only strains with sufficient reads to estimate fitness are shown,
but the strain fitness values are still rather noisy and may be biased towards zero.
Strains near the edge of a gene are not shown as being associated with that
gene (they are in grey).
Strains in the central 10-90% of a gene are color coded by the insertion's strand.
Usually, "+" means that the selectable marker is encoded on the forward strand,
i.e., transcribed rightward.
500 nt Rv0780 and Rv0781 overlap by 4 nucleotides Rv0781 and Rv0782 overlap by 212 nucleotides Rv0782 and Rv0783c are separated by 427 nucleotides
Rv0780: Rv0780 - Phosphoribosylaminoimidazole-succinocarboxamide synthase PurC (SAICAR synthetase), at 873,343 to 874,236
Rv0780
Rv0781: Rv0781 - Probable protease II PtrBa [first part] (oligopeptidase B), at 874,233 to 874,943
Rv0781
Rv0782: Rv0782 - Probable protease II PtrBb [second part] (oligopeptidase B), at 874,732 to 876,390
Rv0782
Rv0783c: Rv0783c - Possible multidrug resistance integral membrane efflux protein EmrB, at 876,818 to 878,440
Rv0783c
Position (kb) 874
875
876
877 Strain fitness (log2 ratio) -1
0
1 at 874.540 kb on + strand, within Rv0781 at 874.713 kb on + strand, within Rv0781 at 875.285 kb on - strand, within Rv0782 at 875.496 kb on + strand, within Rv0782 at 875.546 kb on - strand, within Rv0782 at 875.860 kb on - strand, within Rv0782 at 876.085 kb on + strand, within Rv0782 at 876.320 kb on + strand at 876.325 kb on - strand at 876.419 kb on - strand at 876.462 kb on + strand at 877.269 kb on - strand, within Rv0783c
Per-strain Table
Position Strand Gene LocusTag Fraction 7H9 with Isoniazid 0.025 ug/mL remove 874,540 + Rv0781 0.43 -0.0 874,713 + Rv0781 0.68 -0.1 875,285 - Rv0782 0.33 +0.8 875,496 + Rv0782 0.46 +0.4 875,546 - Rv0782 0.49 +1.6 875,860 - Rv0782 0.68 -0.8 876,085 + Rv0782 0.82 +0.2 876,320 + +0.8 876,325 - -0.1 876,419 - +0.4 876,462 + -0.6 877,269 - Rv0783c 0.28 +0.5
Or see this region's nucleotide sequence