Experiment: 7H9 with Isoniazid 0.025 ug/mL
Only strains with sufficient reads to estimate fitness are shown,
but the strain fitness values are still rather noisy and may be biased towards zero.
Strains near the edge of a gene are not shown as being associated with that
gene (they are in grey).
Strains in the central 10-90% of a gene are color coded by the insertion's strand.
Usually, "+" means that the selectable marker is encoded on the forward strand,
i.e., transcribed rightward.
500 nt Rv0742 and Rv0743c are separated by 377 nucleotides Rv0743c and Rv0744c overlap by 4 nucleotides Rv0744c and Rv0745 are separated by 207 nucleotides
Rv0742: Rv0742 - PE-PGRS family protein PE_PGRS8, at 832,981 to 833,508
Rv0742
Rv0743c: Rv0743c - Hypothetical protein, at 833,886 to 834,443
Rv0743c
Rv0744c: Rv0744c - Possible transcriptional regulatory protein, at 834,440 to 834,946
Rv0744c
Rv0745: Rv0745 - Conserved hypothetical protein, at 835,154 to 835,681
Rv0745
Position (kb) 833
834
835 Strain fitness (log2 ratio) -2
-1
0
1
2
3
4 at 832.950 kb on + strand at 832.983 kb on - strand at 833.200 kb on - strand, within Rv0742 at 833.239 kb on + strand, within Rv0742 at 833.239 kb on + strand, within Rv0742 at 833.240 kb on - strand, within Rv0742 at 833.532 kb on - strand at 833.614 kb on - strand at 833.738 kb on + strand at 833.738 kb on + strand at 833.738 kb on + strand at 833.887 kb on + strand at 833.887 kb on + strand at 833.887 kb on + strand at 833.888 kb on - strand at 833.888 kb on - strand at 833.888 kb on - strand at 833.911 kb on + strand at 833.912 kb on - strand at 833.912 kb on - strand at 833.912 kb on - strand at 833.912 kb on - strand at 833.914 kb on + strand at 833.914 kb on + strand at 833.915 kb on - strand at 833.915 kb on - strand at 833.915 kb on - strand at 834.182 kb on + strand, within Rv0743c at 834.182 kb on + strand, within Rv0743c at 834.182 kb on + strand, within Rv0743c at 834.183 kb on - strand, within Rv0743c at 834.183 kb on - strand, within Rv0743c at 834.183 kb on - strand, within Rv0743c at 834.186 kb on + strand, within Rv0743c at 834.186 kb on + strand, within Rv0743c at 834.186 kb on + strand, within Rv0743c at 834.187 kb on - strand, within Rv0743c at 834.187 kb on - strand, within Rv0743c at 834.187 kb on - strand, within Rv0743c at 834.187 kb on - strand, within Rv0743c at 834.199 kb on + strand, within Rv0743c at 834.327 kb on + strand, within Rv0743c at 834.328 kb on - strand, within Rv0743c at 834.373 kb on - strand, within Rv0743c at 834.524 kb on + strand, within Rv0744c at 834.639 kb on + strand, within Rv0744c at 834.670 kb on + strand, within Rv0744c at 834.909 kb on - strand at 835.016 kb on + strand at 835.017 kb on - strand at 835.060 kb on + strand at 835.061 kb on - strand at 835.130 kb on - strand at 835.222 kb on + strand, within Rv0745
Per-strain Table
Position Strand Gene LocusTag Fraction 7H9 with Isoniazid 0.025 ug/mL remove 832,950 + +0.8 832,983 - +0.1 833,200 - Rv0742 0.41 -0.2 833,239 + Rv0742 0.49 -0.2 833,239 + Rv0742 0.49 -1.2 833,240 - Rv0742 0.49 -2.1 833,532 - -0.3 833,614 - +0.5 833,738 + +0.1 833,738 + -0.1 833,738 + +0.6 833,887 + +1.2 833,887 + -1.0 833,887 + +0.2 833,888 - +0.2 833,888 - +0.1 833,888 - -0.0 833,911 + +0.2 833,912 - +0.8 833,912 - +2.2 833,912 - -0.2 833,912 - +0.5 833,914 + +0.2 833,914 + -0.1 833,915 - -0.1 833,915 - +0.3 833,915 - -0.2 834,182 + Rv0743c 0.53 +0.7 834,182 + Rv0743c 0.53 +0.4 834,182 + Rv0743c 0.53 +0.6 834,183 - Rv0743c 0.53 +0.5 834,183 - Rv0743c 0.53 +0.7 834,183 - Rv0743c 0.53 +0.8 834,186 + Rv0743c 0.54 -0.7 834,186 + Rv0743c 0.54 -0.5 834,186 + Rv0743c 0.54 -0.3 834,187 - Rv0743c 0.54 +1.8 834,187 - Rv0743c 0.54 -0.0 834,187 - Rv0743c 0.54 -1.1 834,187 - Rv0743c 0.54 +0.8 834,199 + Rv0743c 0.56 +4.1 834,327 + Rv0743c 0.79 -0.5 834,328 - Rv0743c 0.79 +0.2 834,373 - Rv0743c 0.87 -0.1 834,524 + Rv0744c 0.17 +0.2 834,639 + Rv0744c 0.39 +0.4 834,670 + Rv0744c 0.45 +0.5 834,909 - +0.3 835,016 + +1.3 835,017 - +1.0 835,060 + +1.1 835,061 - +0.9 835,130 - +1.2 835,222 + Rv0745 0.13 +0.5
Or see this region's nucleotide sequence