Experiment: 7H9 with Isoniazid 0.025 ug/mL
Only strains with sufficient reads to estimate fitness are shown,
but the strain fitness values are still rather noisy and may be biased towards zero.
Strains near the edge of a gene are not shown as being associated with that
gene (they are in grey).
Strains in the central 10-90% of a gene are color coded by the insertion's strand.
Usually, "+" means that the selectable marker is encoded on the forward strand,
i.e., transcribed rightward.
500 nt Rv0708 and Rv0709 overlap by 1 nucleotides Rv0709 and Rv0710 overlap by 4 nucleotides Rv0710 and Rv0711 are separated by 168 nucleotides Rv0711 and Rv0712 are separated by 47 nucleotides
Rv0708: Rv0708 - 50S ribosomal protein L16 RplP, at 805,110 to 805,526
Rv0708
Rv0709: Rv0709 - 50S ribosomal protein L29 RpmC, at 805,526 to 805,759
Rv0709
Rv0710: Rv0710 - 30S ribosomal protein S17 RpsQ, at 805,756 to 806,166
Rv0710
Rv0711: Rv0711 - Possible arylsulfatase AtsA (aryl-sulfate sulphohydrolase) (arylsulphatase), at 806,335 to 808,698
Rv0711
Rv0712: Rv0712 - Conserved protein, at 808,746 to 809,645
Rv0712
Position (kb) 806
807
808
809 Strain fitness (log2 ratio) -2
-1
0
1
2
3
4 at 806.165 kb on - strand at 806.274 kb on + strand at 806.292 kb on + strand at 806.293 kb on - strand at 806.308 kb on - strand at 806.383 kb on - strand at 806.630 kb on + strand, within Rv0711 at 806.640 kb on + strand, within Rv0711 at 806.734 kb on + strand, within Rv0711 at 806.734 kb on + strand, within Rv0711 at 806.734 kb on + strand, within Rv0711 at 806.734 kb on + strand, within Rv0711 at 806.734 kb on + strand, within Rv0711 at 806.734 kb on + strand, within Rv0711 at 806.734 kb on + strand, within Rv0711 at 806.735 kb on - strand, within Rv0711 at 806.735 kb on - strand, within Rv0711 at 806.743 kb on + strand, within Rv0711 at 806.743 kb on + strand, within Rv0711 at 806.743 kb on + strand, within Rv0711 at 806.744 kb on - strand, within Rv0711 at 806.788 kb on - strand, within Rv0711 at 806.839 kb on + strand, within Rv0711 at 806.885 kb on + strand, within Rv0711 at 806.885 kb on + strand, within Rv0711 at 806.887 kb on + strand, within Rv0711 at 806.888 kb on - strand, within Rv0711 at 807.019 kb on + strand, within Rv0711 at 807.080 kb on - strand, within Rv0711 at 807.104 kb on - strand, within Rv0711 at 807.104 kb on - strand, within Rv0711 at 807.183 kb on - strand, within Rv0711 at 807.356 kb on - strand, within Rv0711 at 807.472 kb on + strand, within Rv0711 at 807.532 kb on + strand, within Rv0711 at 807.577 kb on + strand, within Rv0711 at 807.577 kb on + strand, within Rv0711 at 807.578 kb on - strand, within Rv0711 at 807.578 kb on - strand, within Rv0711 at 807.596 kb on - strand, within Rv0711 at 807.682 kb on + strand, within Rv0711 at 807.683 kb on - strand, within Rv0711 at 808.054 kb on + strand, within Rv0711 at 808.055 kb on - strand, within Rv0711 at 808.114 kb on + strand, within Rv0711 at 808.138 kb on + strand, within Rv0711 at 808.139 kb on - strand, within Rv0711 at 808.139 kb on - strand, within Rv0711 at 808.144 kb on + strand, within Rv0711 at 808.145 kb on - strand, within Rv0711 at 808.145 kb on - strand, within Rv0711 at 808.145 kb on - strand, within Rv0711 at 808.319 kb on - strand, within Rv0711 at 808.319 kb on - strand, within Rv0711 at 808.325 kb on - strand, within Rv0711 at 808.582 kb on + strand at 808.582 kb on + strand at 809.054 kb on - strand, within Rv0712 at 809.125 kb on + strand, within Rv0712 at 809.154 kb on + strand, within Rv0712 at 809.232 kb on + strand, within Rv0712 at 809.232 kb on + strand, within Rv0712 at 809.233 kb on - strand, within Rv0712 at 809.233 kb on - strand, within Rv0712 at 809.421 kb on + strand, within Rv0712 at 809.421 kb on + strand, within Rv0712 at 809.422 kb on - strand, within Rv0712 at 809.544 kb on + strand, within Rv0712
Per-strain Table
Position Strand Gene LocusTag Fraction 7H9 with Isoniazid 0.025 ug/mL remove 806,165 - -0.8 806,274 + -0.8 806,292 + +0.3 806,293 - -1.1 806,308 - -1.3 806,383 - -1.2 806,630 + Rv0711 0.12 -0.3 806,640 + Rv0711 0.13 -0.3 806,734 + Rv0711 0.17 +0.4 806,734 + Rv0711 0.17 -1.2 806,734 + Rv0711 0.17 +4.0 806,734 + Rv0711 0.17 +0.6 806,734 + Rv0711 0.17 -0.4 806,734 + Rv0711 0.17 -0.6 806,734 + Rv0711 0.17 -1.6 806,735 - Rv0711 0.17 +0.7 806,735 - Rv0711 0.17 +0.5 806,743 + Rv0711 0.17 -0.3 806,743 + Rv0711 0.17 +0.7 806,743 + Rv0711 0.17 -0.2 806,744 - Rv0711 0.17 +0.3 806,788 - Rv0711 0.19 +1.8 806,839 + Rv0711 0.21 -0.7 806,885 + Rv0711 0.23 -1.1 806,885 + Rv0711 0.23 -1.1 806,887 + Rv0711 0.23 +1.8 806,888 - Rv0711 0.23 +0.0 807,019 + Rv0711 0.29 -0.1 807,080 - Rv0711 0.32 +0.2 807,104 - Rv0711 0.33 +0.2 807,104 - Rv0711 0.33 -0.6 807,183 - Rv0711 0.36 -2.1 807,356 - Rv0711 0.43 -0.5 807,472 + Rv0711 0.48 -0.1 807,532 + Rv0711 0.51 -0.7 807,577 + Rv0711 0.53 +0.2 807,577 + Rv0711 0.53 -1.3 807,578 - Rv0711 0.53 +1.2 807,578 - Rv0711 0.53 +0.1 807,596 - Rv0711 0.53 -0.4 807,682 + Rv0711 0.57 -0.4 807,683 - Rv0711 0.57 +0.2 808,054 + Rv0711 0.73 -1.0 808,055 - Rv0711 0.73 +1.2 808,114 + Rv0711 0.75 -0.5 808,138 + Rv0711 0.76 -0.2 808,139 - Rv0711 0.76 -1.0 808,139 - Rv0711 0.76 +0.2 808,144 + Rv0711 0.77 -0.4 808,145 - Rv0711 0.77 -0.4 808,145 - Rv0711 0.77 -0.6 808,145 - Rv0711 0.77 +0.9 808,319 - Rv0711 0.84 +1.1 808,319 - Rv0711 0.84 -0.3 808,325 - Rv0711 0.84 +0.7 808,582 + -1.2 808,582 + -0.5 809,054 - Rv0712 0.34 -1.1 809,125 + Rv0712 0.42 +1.0 809,154 + Rv0712 0.45 -0.7 809,232 + Rv0712 0.54 -0.8 809,232 + Rv0712 0.54 -0.2 809,233 - Rv0712 0.54 -1.6 809,233 - Rv0712 0.54 -0.2 809,421 + Rv0712 0.75 +1.6 809,421 + Rv0712 0.75 +1.2 809,422 - Rv0712 0.75 -1.1 809,544 + Rv0712 0.89 -0.6
Or see this region's nucleotide sequence