Experiment: 7H9 with Isoniazid 0.025 ug/mL
Only strains with sufficient reads to estimate fitness are shown,
but the strain fitness values are still rather noisy and may be biased towards zero.
Strains near the edge of a gene are not shown as being associated with that
gene (they are in grey).
Strains in the central 10-90% of a gene are color coded by the insertion's strand.
Usually, "+" means that the selectable marker is encoded on the forward strand,
i.e., transcribed rightward.
500 nt Rv0357c and Rv0358 are separated by 90 nucleotides Rv0358 and Rv0359 are separated by 10 nucleotides Rv0359 and Rv0360c are separated by 4 nucleotides Rv0360c and Rv0361 are separated by 82 nucleotides
Rv0357c: Rv0357c - Probable adenylosuccinate synthetase PurA (imp--aspartate ligase) (ADSS) (ampsase), at 435,471 to 436,769
Rv0357c
Rv0358: Rv0358 - Conserved protein, at 436,860 to 437,507
Rv0358
Rv0359: Rv0359 - Probable conserved integral membrane protein, at 437,518 to 438,297
Rv0359
Rv0360c: Rv0360c - Conserved protein, at 438,302 to 438,739
Rv0360c
Rv0361: Rv0361 - Probable conserved membrane protein, at 438,822 to 439,649
Rv0361
Position (kb) 437
438
439 Strain fitness (log2 ratio) -2
-1
0
1
2
3 at 436.798 kb on - strand at 436.830 kb on - strand at 436.830 kb on - strand at 436.830 kb on - strand at 436.863 kb on + strand at 437.642 kb on - strand, within Rv0359 at 437.759 kb on - strand, within Rv0359 at 437.782 kb on + strand, within Rv0359 at 437.863 kb on + strand, within Rv0359 at 437.863 kb on + strand, within Rv0359 at 437.863 kb on + strand, within Rv0359 at 437.864 kb on - strand, within Rv0359 at 437.864 kb on - strand, within Rv0359 at 437.864 kb on - strand, within Rv0359 at 437.864 kb on - strand, within Rv0359 at 437.864 kb on - strand, within Rv0359 at 438.018 kb on - strand, within Rv0359 at 438.018 kb on - strand, within Rv0359 at 438.018 kb on - strand, within Rv0359 at 438.048 kb on - strand, within Rv0359 at 438.048 kb on - strand, within Rv0359 at 438.211 kb on + strand, within Rv0359 at 438.212 kb on - strand, within Rv0359 at 438.285 kb on + strand at 438.285 kb on + strand at 438.366 kb on + strand, within Rv0360c at 438.367 kb on - strand, within Rv0360c at 438.367 kb on - strand, within Rv0360c at 438.423 kb on - strand, within Rv0360c at 438.525 kb on + strand, within Rv0360c at 438.525 kb on + strand, within Rv0360c at 438.532 kb on - strand, within Rv0360c at 438.778 kb on + strand at 438.778 kb on + strand
Per-strain Table
Position Strand Gene LocusTag Fraction 7H9 with Isoniazid 0.025 ug/mL remove 436,798 - -1.5 436,830 - -0.2 436,830 - -0.4 436,830 - +1.8 436,863 + +2.0 437,642 - Rv0359 0.16 -1.6 437,759 - Rv0359 0.31 +0.6 437,782 + Rv0359 0.34 -0.6 437,863 + Rv0359 0.44 -0.1 437,863 + Rv0359 0.44 +1.1 437,863 + Rv0359 0.44 -1.1 437,864 - Rv0359 0.44 +0.2 437,864 - Rv0359 0.44 +0.4 437,864 - Rv0359 0.44 +0.8 437,864 - Rv0359 0.44 +0.4 437,864 - Rv0359 0.44 -1.8 438,018 - Rv0359 0.64 +0.3 438,018 - Rv0359 0.64 +0.1 438,018 - Rv0359 0.64 +0.0 438,048 - Rv0359 0.68 -0.3 438,048 - Rv0359 0.68 +0.2 438,211 + Rv0359 0.89 -2.7 438,212 - Rv0359 0.89 -0.5 438,285 + -0.5 438,285 + -0.0 438,366 + Rv0360c 0.15 -0.6 438,367 - Rv0360c 0.15 -0.0 438,367 - Rv0360c 0.15 +0.8 438,423 - Rv0360c 0.28 -1.0 438,525 + Rv0360c 0.51 +2.8 438,525 + Rv0360c 0.51 +2.8 438,532 - Rv0360c 0.53 +0.5 438,778 + -1.4 438,778 + -1.2
Or see this region's nucleotide sequence