Experiment: 7H9 with Isoniazid 0.025 ug/mL
Only strains with sufficient reads to estimate fitness are shown,
but the strain fitness values are still rather noisy and may be biased towards zero.
Strains near the edge of a gene are not shown as being associated with that
gene (they are in grey).
Strains in the central 10-90% of a gene are color coded by the insertion's strand.
Usually, "+" means that the selectable marker is encoded on the forward strand,
i.e., transcribed rightward.
500 nt Rv0311 and Rv0312 are separated by 154 nucleotides Rv0312 and Rv0313 are separated by 71 nucleotides Rv0313 and Rv0314c are separated by 2 nucleotides
Rv0311: Rv0311 - Unknown protein, at 379,172 to 380,401
Rv0311
Rv0312: Rv0312 - Conserved hypothetical proline and threonine rich protein, at 380,556 to 382,418
Rv0312
Rv0313: Rv0313 - Conserved protein, at 382,490 to 382,876
Rv0313
Rv0314c: Rv0314c - Possible conserved membrane protein, at 382,879 to 383,541
Rv0314c
Position (kb) 380
381
382
383 Strain fitness (log2 ratio) -2
-1
0
1
2 at 380.076 kb on + strand, within Rv0311 at 380.555 kb on + strand at 380.555 kb on + strand at 380.903 kb on - strand, within Rv0312 at 382.032 kb on - strand, within Rv0312 at 382.459 kb on + strand at 382.459 kb on + strand at 382.463 kb on - strand at 382.463 kb on - strand at 382.712 kb on - strand, within Rv0313 at 382.751 kb on + strand, within Rv0313 at 382.751 kb on + strand, within Rv0313 at 382.752 kb on - strand, within Rv0313 at 382.874 kb on + strand at 382.875 kb on - strand at 382.875 kb on - strand at 382.875 kb on - strand at 382.940 kb on + strand at 382.940 kb on + strand at 383.372 kb on + strand, within Rv0314c at 383.372 kb on + strand, within Rv0314c at 383.372 kb on + strand, within Rv0314c at 383.376 kb on + strand, within Rv0314c at 383.376 kb on + strand, within Rv0314c at 383.376 kb on + strand, within Rv0314c at 383.377 kb on - strand, within Rv0314c at 383.377 kb on - strand, within Rv0314c at 383.405 kb on + strand, within Rv0314c at 383.406 kb on - strand, within Rv0314c at 383.412 kb on - strand, within Rv0314c at 383.412 kb on - strand, within Rv0314c
Per-strain Table
Position Strand Gene LocusTag Fraction 7H9 with Isoniazid 0.025 ug/mL remove 380,076 + Rv0311 0.73 +0.4 380,555 + +0.3 380,555 + +0.6 380,903 - Rv0312 0.19 -0.2 382,032 - Rv0312 0.79 -1.0 382,459 + -0.2 382,459 + -0.1 382,463 - +1.4 382,463 - -0.5 382,712 - Rv0313 0.57 +0.0 382,751 + Rv0313 0.67 -1.3 382,751 + Rv0313 0.67 +0.8 382,752 - Rv0313 0.68 +0.8 382,874 + +1.8 382,875 - -1.8 382,875 - +0.5 382,875 - +0.5 382,940 + +1.6 382,940 + -0.2 383,372 + Rv0314c 0.74 +1.8 383,372 + Rv0314c 0.74 -0.6 383,372 + Rv0314c 0.74 +1.2 383,376 + Rv0314c 0.75 -1.0 383,376 + Rv0314c 0.75 -1.2 383,376 + Rv0314c 0.75 -0.1 383,377 - Rv0314c 0.75 +0.7 383,377 - Rv0314c 0.75 -2.4 383,405 + Rv0314c 0.79 -1.5 383,406 - Rv0314c 0.79 -0.6 383,412 - Rv0314c 0.80 -0.2 383,412 - Rv0314c 0.80 -0.8
Or see this region's nucleotide sequence