Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv0270

Experiment: 7H9 with Isoniazid 0.025 ug/mL

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

Per-strain Table

Position	Strand	Gene	LocusTag	Fraction	7H9 with Isoniazid 0.025 ug/mL
323,979	-		Rv0269c	0.54	+0.6
324,248	+		Rv0269c	0.76	+0.3
324,248	+		Rv0269c	0.76	-0.9
324,398	+		Rv0269c	0.89	-1.8
324,399	-		Rv0269c	0.89	-2.9
324,401	+		Rv0269c	0.89	+1.8
324,425	+				+0.8
324,425	+				+1.5
324,534	+				+3.1
324,556	-				+2.8
324,556	-				-0.2
324,573	-				+1.8
324,630	+				-0.8
324,630	+				-0.2
324,630	+				-2.9
324,661	-				-0.4
324,714	+				-0.3
324,715	-				+0.8
324,875	-		Rv0270	0.18	-0.8
324,875	-		Rv0270	0.18	-0.5
324,952	-		Rv0270	0.23	-0.2
325,056	+		Rv0270	0.29	-1.5
325,057	-		Rv0270	0.29	-1.7
325,068	+		Rv0270	0.30	+0.8
325,069	-		Rv0270	0.30	-0.6
325,507	+		Rv0270	0.56	-0.7
325,508	-		Rv0270	0.56	-0.7
325,508	-		Rv0270	0.56	-0.7
325,508	-		Rv0270	0.56	+1.2
325,656	+		Rv0270	0.65	-1.9
325,666	-		Rv0270	0.65	+0.5
325,909	-		Rv0270	0.80	-2.2
325,932	+		Rv0270	0.81	-0.8
325,933	-		Rv0270	0.81	-0.4
325,933	-		Rv0270	0.81	-1.8
326,058	-		Rv0270	0.89	-1.2
326,136	+				-0.8
326,137	-				-1.3
326,140	+				+0.2
326,141	-				-1.9
326,160	+				-0.8
326,160	+				-0.2
326,198	-				-0.3
326,237	-				-0.1
326,247	+				-1.7
326,247	+				+0.0
326,247	+				-0.2
326,267	+				+0.7
326,282	-				-0.5
326,282	-				-0.5
326,336	+				-0.5
326,336	+				+0.4
326,367	-				+0.6
326,367	-				+0.1
326,447	+				-0.1
326,625	-		Rv0271c	0.16	+0.8
326,786	+		Rv0271c	0.24	+0.0
326,787	-		Rv0271c	0.24	-0.8
326,937	-		Rv0271c	0.31	-0.2