Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv3922c

Experiment: 7H9 with Levofloxacin 0.3 ug/mL

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv3921c and Rv3922c overlap by 17 nucleotidesRv3922c and Rv3923c overlap by 4 nucleotidesRv3923c and Rv3924c overlap by 4 nucleotides Rv3921c: Rv3921c - Probable conserved transmembrane protein, at 4,408,969 to 4,410,069 Rv3921c Rv3922c: Rv3922c - Possible hemolysin, at 4,410,053 to 4,410,415 Rv3922c Rv3923c: Rv3923c - Ribonuclease P protein component RnpA (RNaseP protein) (RNase P protein) (protein C5), at 4,410,412 to 4,410,789 Rv3923c Rv3924c: Rv3924c - 50S ribosomal protein L34 RpmH, at 4,410,786 to 4,410,929 Rv3924c Position (kb) 4410 4411Strain fitness (log2 ratio) -2 -1 0 1at 4410.241 kb on - strand, within Rv3922cat 4410.265 kb on - strand, within Rv3922cat 4410.272 kb on - strand, within Rv3922cat 4410.272 kb on - strand, within Rv3922cat 4410.272 kb on - strand, within Rv3922cat 4410.278 kb on - strand, within Rv3922cat 4410.368 kb on - strand, within Rv3922cat 4410.770 kb on - strandat 4411.182 kb on + strandat 4411.258 kb on + strandat 4411.273 kb on + strand

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Levofloxacin 0.3 ug/mL
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4,410,241 - Rv3922c 0.52 -1.6
4,410,265 - Rv3922c 0.58 -0.6
4,410,272 - Rv3922c 0.60 +0.4
4,410,272 - Rv3922c 0.60 -1.0
4,410,272 - Rv3922c 0.60 -0.8
4,410,278 - Rv3922c 0.62 -0.7
4,410,368 - Rv3922c 0.87 +1.4
4,410,770 - -0.6
4,411,182 + -0.8
4,411,258 + -0.6
4,411,273 + -2.5

Or see this region's nucleotide sequence