Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv3787c

Experiment: 7H9 with Levofloxacin 0.3 ug/mL

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

Per-strain Table

Position	Strand	Gene	LocusTag	Fraction	7H9 with Levofloxacin 0.3 ug/mL
4,232,635	+		Rv3786c	0.21	+1.0
4,232,635	+		Rv3786c	0.21	-0.6
4,232,635	+		Rv3786c	0.21	-1.4
4,232,636	-		Rv3786c	0.21	-0.5
4,232,636	-		Rv3786c	0.21	-1.7
4,232,636	-		Rv3786c	0.21	-0.4
4,232,639	+		Rv3786c	0.22	-1.5
4,232,639	+		Rv3786c	0.22	+0.0
4,232,639	+		Rv3786c	0.22	-0.8
4,232,639	+		Rv3786c	0.22	-0.7
4,232,639	+		Rv3786c	0.22	+0.3
4,232,639	+		Rv3786c	0.22	-0.5
4,232,640	-		Rv3786c	0.22	-0.8
4,232,640	-		Rv3786c	0.22	-1.2
4,232,886	-		Rv3786c	0.42	-0.9
4,232,921	+		Rv3786c	0.45	-1.7
4,232,945	+		Rv3786c	0.47	-0.4
4,232,946	-		Rv3786c	0.47	-0.7
4,232,946	-		Rv3786c	0.47	+0.4
4,232,990	+		Rv3786c	0.50	+0.5
4,232,990	+		Rv3786c	0.50	+0.5
4,233,144	-		Rv3786c	0.63	-0.5
4,233,144	-		Rv3786c	0.63	-1.7
4,233,166	+		Rv3786c	0.65	+0.5
4,233,366	-		Rv3786c	0.81	-1.3
4,233,366	-		Rv3786c	0.81	-0.1
4,233,506	+				-0.5
4,233,506	+				-1.1
4,233,507	-				-1.2
4,233,507	-				+1.3
4,233,609	-				-1.2
4,233,609	-				-1.1
4,233,633	-				+0.2
4,233,633	-				-0.6
4,233,633	-				-1.1
4,233,633	-				+0.4
4,233,633	-				+1.3
4,233,968	+		Rv3787c	0.39	-0.9
4,234,165	-		Rv3787c	0.60	-0.6
4,234,165	-		Rv3787c	0.60	-0.6
4,234,271	+		Rv3787c	0.71	-1.5
4,234,272	-		Rv3787c	0.71	-0.0
4,234,505	-				-0.5
4,234,505	-				+0.2
4,234,505	-				-0.3
4,234,505	-				-0.8
4,234,516	-				-0.5
4,234,516	-				+0.0
4,234,596	+				+2.0
4,234,614	-				-0.9
4,234,634	-				-0.5
4,234,634	-				-0.7
4,234,641	+				+0.5
4,234,641	+				-0.1
4,234,641	+				+0.6
4,234,642	-				+0.4
4,234,642	-				+0.0
4,234,669	-				-0.0
4,234,669	-				-2.0
4,234,669	-				-0.2
4,234,710	+				+2.0
4,234,714	-				-0.7
4,234,714	-				-0.6
4,234,714	-				+0.2
4,234,717	+				+0.4
4,234,938	-		Rv3788	0.33	-0.9
4,234,938	-		Rv3788	0.33	-1.2
4,235,096	+		Rv3788	0.65	-0.4
4,235,096	+		Rv3788	0.65	-0.6
4,235,096	+		Rv3788	0.65	-0.1
4,235,096	+		Rv3788	0.65	-0.0
4,235,096	+		Rv3788	0.65	-0.8
4,235,096	+		Rv3788	0.65	-1.1
4,235,096	+		Rv3788	0.65	-0.8
4,235,097	-		Rv3788	0.65	-0.0
4,235,162	+		Rv3788	0.79	-1.0
4,235,162	+		Rv3788	0.79	+1.3
4,235,163	-		Rv3788	0.79	-0.1
4,235,226	+				-0.8
4,235,226	+				-0.7
4,235,263	+				-1.7
4,235,264	-				-0.5
4,235,372	+				+1.0
4,235,372	+				-0.7