Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv3678c

Experiment: 7H9 with Levofloxacin 0.3 ug/mL

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

Per-strain Table

Position	Strand	Gene	LocusTag	Fraction	7H9 with Levofloxacin 0.3 ug/mL
4,117,184	+				-0.4
4,117,185	-				-1.2
4,117,185	-				-0.4
4,117,275	-				-0.8
4,117,399	+		Rv3677c	0.18	-0.6
4,117,399	+		Rv3677c	0.18	+4.0
4,117,400	-		Rv3677c	0.18	-0.5
4,117,532	+		Rv3677c	0.34	-0.4
4,117,532	+		Rv3677c	0.34	+1.0
4,117,532	+		Rv3677c	0.34	-0.2
4,117,533	-		Rv3677c	0.35	+0.4
4,117,540	+		Rv3677c	0.35	-0.7
4,117,665	+		Rv3677c	0.51	+2.0
4,117,666	-		Rv3677c	0.51	-0.6
4,118,108	-		Rv3678c	0.11	-0.2
4,118,445	-		Rv3678c	0.85	+3.0
4,118,524	+				+2.0
4,118,525	-				+0.2
4,118,532	-				-0.8
4,118,532	-				+0.2
4,118,549	+		Rv3678A	0.12	+2.0
4,118,666	+		Rv3678A	0.84	+0.2
4,118,666	+		Rv3678A	0.84	-0.1
4,118,703	-				+0.1
4,118,767	+				+1.2
4,118,767	+				+0.4