Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv3661

Experiment: 7H9 with Levofloxacin 0.3 ug/mL

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

Per-strain Table

Position	Strand	Gene	LocusTag	Fraction	7H9 with Levofloxacin 0.3 ug/mL
4,099,349	+				+0.2
4,099,455	+				-1.2
4,099,455	+				+0.1
4,099,484	+				+2.0
4,099,485	-				+0.1
4,099,488	-				+0.4
4,099,488	-				-1.9
4,099,488	-				-1.5
4,099,518	-				-0.2
4,099,552	+				-2.2
4,099,553	-				+0.1
4,099,635	+				-1.6
4,099,635	+				-1.4
4,099,636	-				+0.4
4,099,839	+		Rv3661	0.22	-2.0
4,099,934	-		Rv3661	0.33	-0.8
4,100,169	+		Rv3661	0.60	-1.5
4,100,170	-		Rv3661	0.61	-1.5
4,100,170	-		Rv3661	0.61	-1.0
4,100,186	+		Rv3661	0.62	-0.8
4,100,245	-		Rv3661	0.69	-1.0
4,100,251	-		Rv3661	0.70	-0.7
4,100,475	+				-1.6
4,100,475	+				+2.2
4,100,476	-				-0.3
4,100,476	-				-0.0
4,100,482	+				-0.2
4,100,485	+				+0.2
4,100,485	+				-3.0
4,100,666	+				-0.7
4,100,669	+				+0.2
4,100,669	+				-1.0
4,100,673	-				-0.4
4,100,861	-				+0.3
4,100,999	-				-1.1
4,101,041	+				+0.6
4,101,041	+				-1.0
4,101,042	-				-0.5
4,101,042	-				-1.4
4,101,042	-				-0.6
4,101,263	-				+1.2