Experiment: 7H9 with Levofloxacin 0.3 ug/mL
Only strains with sufficient reads to estimate fitness are shown,
but the strain fitness values are still rather noisy and may be biased towards zero.
Strains near the edge of a gene are not shown as being associated with that
gene (they are in grey).
Strains in the central 10-90% of a gene are color coded by the insertion's strand.
Usually, "+" means that the selectable marker is encoded on the forward strand,
i.e., transcribed rightward.
500 nt Rv3651 and Rv3652 are separated by 753 nucleotides Rv3652 and Rv3653 overlap by 7 nucleotides Rv3653 and Rv3654c are separated by 132 nucleotides Rv3654c and Rv3655c are separated by 8 nucleotides
Rv3651: Rv3651 - Conserved hypothetical protein, at 4,091,841 to 4,092,878
Rv3651
Rv3652: Rv3652 - PE-PGRS family-related protein PE_PGRS60, at 4,093,632 to 4,093,946
Rv3652
Rv3653: Rv3653 - PE-PGRS family-related protein PE_PGRS61, at 4,093,940 to 4,094,527
Rv3653
Rv3654c: Rv3654c - Conserved hypothetical protein, at 4,094,660 to 4,094,914
Rv3654c
Rv3655c: Rv3655c - Conserved hypothetical protein, at 4,094,923 to 4,095,300
Rv3655c
Position (kb)
4093
4094 Strain fitness (log2 ratio)
-2
-1
0
1 at 4093.553 kb on + strand at 4093.638 kb on + strand at 4093.638 kb on + strand at 4093.638 kb on + strand at 4093.792 kb on - strand, within Rv3652 at 4093.814 kb on + strand, within Rv3652 at 4093.814 kb on + strand, within Rv3652 at 4093.815 kb on - strand, within Rv3652 at 4094.562 kb on - strand at 4094.585 kb on - strand at 4094.613 kb on - strand at 4094.613 kb on - strand at 4094.650 kb on + strand at 4094.924 kb on + strand at 4094.924 kb on + strand at 4094.929 kb on - strand
Per-strain Table
Position Strand Gene LocusTag Fraction 7H9 with Levofloxacin 0.3 ug/mL remove 4,093,553 + -1.9 4,093,638 + -0.4 4,093,638 + -0.2 4,093,638 + -0.4 4,093,792 - Rv3652 0.51 -1.0 4,093,814 + Rv3652 0.58 -1.2 4,093,814 + Rv3652 0.58 -0.6 4,093,815 - Rv3652 0.58 -0.6 4,094,562 - -0.5 4,094,585 - -0.9 4,094,613 - -0.7 4,094,613 - -0.1 4,094,650 + -1.4 4,094,924 + -0.2 4,094,924 + -0.7 4,094,929 - -0.3
Or see this region's nucleotide sequence