Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv3585

Experiment: 7H9 with Levofloxacin 0.3 ug/mL

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

Per-strain Table

Position	Strand	Gene	LocusTag	Fraction	7H9 with Levofloxacin 0.3 ug/mL
4,025,576	-				+1.0
4,025,624	-				-0.0
4,025,624	-				+0.8
4,025,762	+				+0.2
4,025,762	+				-1.2
4,025,763	-				-0.2
4,025,763	-				-1.0
4,025,763	-				-0.4
4,025,763	-				+0.0
4,025,766	+				+0.2
4,025,766	+				-0.8
4,025,766	+				-1.5
4,025,767	-				+0.1
4,025,767	-				-0.3
4,025,767	-				+2.0
4,025,769	+				+0.4
4,025,769	+				-0.4
4,025,770	-				-1.5
4,026,074	+		Rv3584	0.44	-0.0
4,026,074	+		Rv3584	0.44	+0.6
4,026,259	-		Rv3584	0.78	-0.5
4,026,292	+		Rv3584	0.84	-1.3
4,026,335	+				-1.5
4,026,335	+				-1.1
4,026,466	-				-3.3
4,026,541	+				+2.0
4,026,542	-				-1.0
4,026,685	+		Rv3585	0.17	-3.1
4,026,685	+		Rv3585	0.17	-1.3
4,026,686	-		Rv3585	0.17	-1.3
4,026,804	+		Rv3585	0.25	+4.3
4,026,804	+		Rv3585	0.25	-1.1
4,026,804	+		Rv3585	0.25	-1.1
4,026,805	-		Rv3585	0.25	-1.5
4,026,885	+		Rv3585	0.31	-0.9
4,026,886	-		Rv3585	0.31	-1.0
4,027,506	+		Rv3585	0.74	+0.6
4,027,506	+		Rv3585	0.74	-0.6
4,027,506	+		Rv3585	0.74	+2.6
4,027,506	+		Rv3585	0.74	-1.4
4,027,507	-		Rv3585	0.74	-1.2
4,027,507	-		Rv3585	0.74	-1.5
4,027,507	-		Rv3585	0.74	-1.5
4,027,507	-		Rv3585	0.74	-0.5
4,027,507	-		Rv3585	0.74	+3.0
4,027,631	-		Rv3585	0.82	-1.8
4,027,791	+				-0.6
4,027,791	+				+0.4
4,027,791	+				-0.8
4,027,791	+				-0.3
4,027,791	+				-2.5
4,027,792	-				+0.4
4,027,792	-				+1.0
4,027,792	-				-1.5
4,027,870	+				-0.8
4,027,880	+				+0.2
4,027,880	+				-2.7
4,027,880	+				-0.5
4,027,880	+				-0.2
4,027,881	-				-1.3
4,027,881	-				-0.8
4,027,884	+				+0.6
4,027,884	+				-0.0
4,027,974	+				-0.7
4,028,068	+		Rv3586	0.16	-0.6
4,028,068	+		Rv3586	0.16	-0.8
4,028,288	-		Rv3586	0.37	+2.0
4,028,371	+		Rv3586	0.45	-0.5
4,028,504	-		Rv3586	0.57	-1.1
4,028,504	-		Rv3586	0.57	-0.9
4,028,770	+		Rv3586	0.82	+0.0