Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv3202c

Experiment: 7H9 with Levofloxacin 0.3 ug/mL

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv3201c and Rv3202c overlap by 4 nucleotidesRv3202c and Rv3203 are separated by 437 nucleotides Rv3201c: Rv3201c - Probable ATP-dependent DNA helicase, at 3,573,731 to 3,577,036 Rv3201c Rv3202c: Rv3202c - Possible ATP-dependent DNA helicase, at 3,577,033 to 3,580,200 Rv3202c Rv3203: Rv3203 - Possible lipase LipV, at 3,580,638 to 3,581,312 Rv3203 Position (kb) 3577 3578 3579 3580 3581Strain fitness (log2 ratio) -6 -5 -4 -3 -2 -1 0 1 2 3at 3576.081 kb on + strand, within Rv3201cat 3576.082 kb on - strand, within Rv3201cat 3576.189 kb on + strand, within Rv3201cat 3576.189 kb on + strand, within Rv3201cat 3576.189 kb on + strand, within Rv3201cat 3576.415 kb on - strand, within Rv3201cat 3576.672 kb on - strand, within Rv3201cat 3576.694 kb on - strand, within Rv3201cat 3576.993 kb on - strandat 3577.238 kb on + strandat 3577.238 kb on + strandat 3577.238 kb on + strandat 3577.239 kb on - strandat 3577.304 kb on + strandat 3577.531 kb on + strand, within Rv3202cat 3577.973 kb on - strand, within Rv3202cat 3578.318 kb on - strand, within Rv3202cat 3578.355 kb on + strand, within Rv3202cat 3578.471 kb on + strand, within Rv3202cat 3578.471 kb on + strand, within Rv3202cat 3578.472 kb on - strand, within Rv3202cat 3578.472 kb on - strand, within Rv3202cat 3578.602 kb on + strand, within Rv3202cat 3578.602 kb on + strand, within Rv3202cat 3579.479 kb on - strand, within Rv3202cat 3579.849 kb on + strand, within Rv3202cat 3579.849 kb on + strand, within Rv3202cat 3579.849 kb on + strand, within Rv3202cat 3579.905 kb on + strandat 3579.905 kb on + strandat 3579.905 kb on + strandat 3579.911 kb on + strandat 3579.911 kb on + strandat 3579.912 kb on - strandat 3579.912 kb on - strandat 3579.912 kb on - strandat 3579.928 kb on + strandat 3580.110 kb on + strandat 3580.191 kb on + strandat 3580.191 kb on + strandat 3580.191 kb on + strandat 3580.191 kb on + strandat 3580.200 kb on + strandat 3580.299 kb on + strandat 3580.324 kb on - strandat 3580.394 kb on + strandat 3580.493 kb on + strandat 3580.494 kb on - strandat 3580.545 kb on + strandat 3580.545 kb on + strandat 3580.683 kb on - strandat 3580.683 kb on - strandat 3580.805 kb on + strand, within Rv3203at 3580.806 kb on - strand, within Rv3203at 3581.166 kb on + strand, within Rv3203at 3581.166 kb on + strand, within Rv3203

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Levofloxacin 0.3 ug/mL
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3,576,081 + Rv3201c 0.71 -3.1
3,576,082 - Rv3201c 0.71 -0.4
3,576,189 + Rv3201c 0.74 -3.7
3,576,189 + Rv3201c 0.74 +1.8
3,576,189 + Rv3201c 0.74 -3.3
3,576,415 - Rv3201c 0.81 -1.3
3,576,672 - Rv3201c 0.89 +3.1
3,576,694 - Rv3201c 0.90 -1.4
3,576,993 - +0.6
3,577,238 + -2.0
3,577,238 + +1.6
3,577,238 + -0.4
3,577,239 - +2.1
3,577,304 + -3.5
3,577,531 + Rv3202c 0.16 -1.3
3,577,973 - Rv3202c 0.30 -2.2
3,578,318 - Rv3202c 0.41 -3.4
3,578,355 + Rv3202c 0.42 -2.3
3,578,471 + Rv3202c 0.45 -0.9
3,578,471 + Rv3202c 0.45 -2.7
3,578,472 - Rv3202c 0.45 -3.7
3,578,472 - Rv3202c 0.45 -3.1
3,578,602 + Rv3202c 0.50 +2.1
3,578,602 + Rv3202c 0.50 -3.6
3,579,479 - Rv3202c 0.77 -3.3
3,579,849 + Rv3202c 0.89 -2.0
3,579,849 + Rv3202c 0.89 -4.4
3,579,849 + Rv3202c 0.89 -1.2
3,579,905 + -2.6
3,579,905 + -1.8
3,579,905 + -0.3
3,579,911 + -2.9
3,579,911 + -0.9
3,579,912 - -3.5
3,579,912 - -1.0
3,579,912 - -1.2
3,579,928 + -2.5
3,580,110 + -1.7
3,580,191 + -2.6
3,580,191 + -5.8
3,580,191 + -3.2
3,580,191 + -0.9
3,580,200 + -0.5
3,580,299 + -0.9
3,580,324 - +0.1
3,580,394 + -0.5
3,580,493 + -0.2
3,580,494 - -0.8
3,580,545 + -1.6
3,580,545 + +2.1
3,580,683 - +0.2
3,580,683 - -0.4
3,580,805 + Rv3203 0.25 -0.8
3,580,806 - Rv3203 0.25 +0.5
3,581,166 + Rv3203 0.78 +1.4
3,581,166 + Rv3203 0.78 -0.7

Or see this region's nucleotide sequence