Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv3201c

Experiment: 7H9 with Levofloxacin 0.3 ug/mL

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv3200c and Rv3201c are separated by 61 nucleotidesRv3201c and Rv3202c overlap by 4 nucleotides Rv3200c: Rv3200c - Possible transmembrane cation transporter, at 3,572,602 to 3,573,669 Rv3200c Rv3201c: Rv3201c - Probable ATP-dependent DNA helicase, at 3,573,731 to 3,577,036 Rv3201c Rv3202c: Rv3202c - Possible ATP-dependent DNA helicase, at 3,577,033 to 3,580,200 Rv3202c Position (kb) 3573 3574 3575 3576 3577 3578Strain fitness (log2 ratio) -3 -2 -1 0 1 2 3at 3573.160 kb on + strand, within Rv3200cat 3573.226 kb on - strand, within Rv3200cat 3573.226 kb on - strand, within Rv3200cat 3573.428 kb on + strand, within Rv3200cat 3573.429 kb on - strand, within Rv3200cat 3573.429 kb on - strand, within Rv3200cat 3573.495 kb on - strand, within Rv3200cat 3573.661 kb on - strandat 3573.724 kb on - strandat 3573.767 kb on + strandat 3573.768 kb on - strandat 3573.768 kb on - strandat 3573.795 kb on - strandat 3573.832 kb on - strandat 3573.834 kb on + strandat 3573.834 kb on + strandat 3573.834 kb on + strandat 3573.835 kb on - strandat 3573.835 kb on - strandat 3573.844 kb on + strandat 3573.844 kb on + strandat 3573.895 kb on - strandat 3574.195 kb on - strand, within Rv3201cat 3574.759 kb on + strand, within Rv3201cat 3575.127 kb on + strand, within Rv3201cat 3575.128 kb on - strand, within Rv3201cat 3575.300 kb on + strand, within Rv3201cat 3575.304 kb on - strand, within Rv3201cat 3575.660 kb on + strand, within Rv3201cat 3575.661 kb on - strand, within Rv3201cat 3575.661 kb on - strand, within Rv3201cat 3575.940 kb on - strand, within Rv3201cat 3575.940 kb on - strand, within Rv3201cat 3576.024 kb on - strand, within Rv3201cat 3576.081 kb on + strand, within Rv3201cat 3576.082 kb on - strand, within Rv3201cat 3576.189 kb on + strand, within Rv3201cat 3576.189 kb on + strand, within Rv3201cat 3576.189 kb on + strand, within Rv3201cat 3576.415 kb on - strand, within Rv3201cat 3576.672 kb on - strand, within Rv3201cat 3576.694 kb on - strand, within Rv3201cat 3576.993 kb on - strandat 3577.238 kb on + strandat 3577.238 kb on + strandat 3577.238 kb on + strandat 3577.239 kb on - strandat 3577.304 kb on + strandat 3577.531 kb on + strand, within Rv3202cat 3577.973 kb on - strand, within Rv3202c

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Levofloxacin 0.3 ug/mL
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3,573,160 + Rv3200c 0.52 +0.1
3,573,226 - Rv3200c 0.58 -2.7
3,573,226 - Rv3200c 0.58 -2.3
3,573,428 + Rv3200c 0.77 +0.0
3,573,429 - Rv3200c 0.77 -1.7
3,573,429 - Rv3200c 0.77 +2.1
3,573,495 - Rv3200c 0.84 -1.0
3,573,661 - +0.2
3,573,724 - -0.5
3,573,767 + -0.9
3,573,768 - -1.2
3,573,768 - -1.3
3,573,795 - -2.4
3,573,832 - -2.0
3,573,834 + -3.1
3,573,834 + +0.5
3,573,834 + -2.1
3,573,835 - -2.0
3,573,835 - -0.5
3,573,844 + -2.9
3,573,844 + -3.1
3,573,895 - +1.1
3,574,195 - Rv3201c 0.14 -0.2
3,574,759 + Rv3201c 0.31 -2.8
3,575,127 + Rv3201c 0.42 +2.1
3,575,128 - Rv3201c 0.42 -1.7
3,575,300 + Rv3201c 0.47 +0.3
3,575,304 - Rv3201c 0.48 -1.6
3,575,660 + Rv3201c 0.58 -0.9
3,575,661 - Rv3201c 0.58 -0.4
3,575,661 - Rv3201c 0.58 +0.1
3,575,940 - Rv3201c 0.67 -2.4
3,575,940 - Rv3201c 0.67 +0.1
3,576,024 - Rv3201c 0.69 -1.0
3,576,081 + Rv3201c 0.71 -3.1
3,576,082 - Rv3201c 0.71 -0.4
3,576,189 + Rv3201c 0.74 -3.7
3,576,189 + Rv3201c 0.74 +1.8
3,576,189 + Rv3201c 0.74 -3.3
3,576,415 - Rv3201c 0.81 -1.3
3,576,672 - Rv3201c 0.89 +3.1
3,576,694 - Rv3201c 0.90 -1.4
3,576,993 - +0.6
3,577,238 + -2.0
3,577,238 + +1.6
3,577,238 + -0.4
3,577,239 - +2.1
3,577,304 + -3.5
3,577,531 + Rv3202c 0.16 -1.3
3,577,973 - Rv3202c 0.30 -2.2

Or see this region's nucleotide sequence