Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv3200c

Experiment: 7H9 with Levofloxacin 0.3 ug/mL

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv3199c and Rv3200c are separated by 58 nucleotidesRv3200c and Rv3201c are separated by 61 nucleotides Rv3199c: Rv3199c - Probable NADH pyrophosphatase NudC (NAD+ diphosphatase) (NAD+ pyrophosphatase) (NADP pyrophosphatase), at 3,571,602 to 3,572,543 Rv3199c Rv3200c: Rv3200c - Possible transmembrane cation transporter, at 3,572,602 to 3,573,669 Rv3200c Rv3201c: Rv3201c - Probable ATP-dependent DNA helicase, at 3,573,731 to 3,577,036 Rv3201c Position (kb) 3572 3573 3574Strain fitness (log2 ratio) -3 -2 -1 0 1 2at 3571.850 kb on - strand, within Rv3199cat 3572.115 kb on + strand, within Rv3199cat 3572.235 kb on + strand, within Rv3199cat 3572.235 kb on + strand, within Rv3199cat 3572.236 kb on - strand, within Rv3199cat 3572.236 kb on - strand, within Rv3199cat 3572.236 kb on - strand, within Rv3199cat 3572.313 kb on + strand, within Rv3199cat 3572.313 kb on + strand, within Rv3199cat 3572.533 kb on - strandat 3572.533 kb on - strandat 3572.533 kb on - strandat 3572.603 kb on + strandat 3572.624 kb on + strandat 3572.625 kb on - strandat 3572.625 kb on - strandat 3572.625 kb on - strandat 3572.696 kb on - strandat 3572.696 kb on - strandat 3573.160 kb on + strand, within Rv3200cat 3573.226 kb on - strand, within Rv3200cat 3573.226 kb on - strand, within Rv3200cat 3573.428 kb on + strand, within Rv3200cat 3573.429 kb on - strand, within Rv3200cat 3573.429 kb on - strand, within Rv3200cat 3573.495 kb on - strand, within Rv3200cat 3573.661 kb on - strandat 3573.724 kb on - strandat 3573.767 kb on + strandat 3573.768 kb on - strandat 3573.768 kb on - strandat 3573.795 kb on - strandat 3573.832 kb on - strandat 3573.834 kb on + strandat 3573.834 kb on + strandat 3573.834 kb on + strandat 3573.835 kb on - strandat 3573.835 kb on - strandat 3573.844 kb on + strandat 3573.844 kb on + strandat 3573.895 kb on - strandat 3574.195 kb on - strand, within Rv3201c

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Levofloxacin 0.3 ug/mL
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3,571,850 - Rv3199c 0.26 +0.6
3,572,115 + Rv3199c 0.54 -0.2
3,572,235 + Rv3199c 0.67 +2.7
3,572,235 + Rv3199c 0.67 -0.5
3,572,236 - Rv3199c 0.67 +0.5
3,572,236 - Rv3199c 0.67 +1.1
3,572,236 - Rv3199c 0.67 -0.3
3,572,313 + Rv3199c 0.75 -0.3
3,572,313 + Rv3199c 0.75 -0.6
3,572,533 - -0.0
3,572,533 - +0.4
3,572,533 - +1.0
3,572,603 + +0.1
3,572,624 + -1.0
3,572,625 - -1.1
3,572,625 - +2.1
3,572,625 - -0.0
3,572,696 - -0.5
3,572,696 - -1.3
3,573,160 + Rv3200c 0.52 +0.1
3,573,226 - Rv3200c 0.58 -2.7
3,573,226 - Rv3200c 0.58 -2.3
3,573,428 + Rv3200c 0.77 +0.0
3,573,429 - Rv3200c 0.77 -1.7
3,573,429 - Rv3200c 0.77 +2.1
3,573,495 - Rv3200c 0.84 -1.0
3,573,661 - +0.2
3,573,724 - -0.5
3,573,767 + -0.9
3,573,768 - -1.2
3,573,768 - -1.3
3,573,795 - -2.4
3,573,832 - -2.0
3,573,834 + -3.1
3,573,834 + +0.5
3,573,834 + -2.1
3,573,835 - -2.0
3,573,835 - -0.5
3,573,844 + -2.9
3,573,844 + -3.1
3,573,895 - +1.1
3,574,195 - Rv3201c 0.14 -0.2

Or see this region's nucleotide sequence