Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv3075c

Experiment: 7H9 with Levofloxacin 0.3 ug/mL

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

Per-strain Table

Position	Strand	Gene	LocusTag	Fraction	7H9 with Levofloxacin 0.3 ug/mL
3,437,162	-		Rv3074	0.30	+0.3
3,437,174	-		Rv3074	0.31	+0.9
3,437,174	-		Rv3074	0.31	+1.2
3,437,174	-		Rv3074	0.31	-1.0
3,437,174	-		Rv3074	0.31	-0.3
3,437,245	-		Rv3074	0.37	-0.5
3,437,300	+		Rv3074	0.41	+0.4
3,437,300	+		Rv3074	0.41	-0.9
3,437,300	+		Rv3074	0.41	-0.2
3,437,337	+		Rv3074	0.44	-0.1
3,437,337	+		Rv3074	0.44	-0.0
3,437,337	+		Rv3074	0.44	-0.1
3,437,338	-		Rv3074	0.44	-0.0
3,437,379	+		Rv3074	0.47	-1.0
3,437,379	+		Rv3074	0.47	-0.7
3,437,379	+		Rv3074	0.47	-0.6
3,437,655	+		Rv3074	0.69	+0.0
3,437,656	-		Rv3074	0.69	-2.3
3,437,656	-		Rv3074	0.69	-0.1
3,437,766	+		Rv3074	0.77	+0.5
3,437,767	-		Rv3074	0.77	-1.4
3,438,054	+				-0.6
3,438,060	+				+1.2
3,438,123	+				-0.9
3,438,592	+		Rv3075c	0.59	-0.6
3,438,592	+		Rv3075c	0.59	-1.4
3,438,592	+		Rv3075c	0.59	+0.4
3,438,592	+		Rv3075c	0.59	-0.8
3,438,592	+		Rv3075c	0.59	-2.4
3,438,593	-		Rv3075c	0.59	+0.4
3,438,683	+		Rv3075c	0.69	-2.5
3,438,960	+				-0.3
3,438,960	+				-0.4
3,438,960	+				-1.2
3,438,960	+				-0.1
3,438,976	-				-1.9
3,439,015	+				+0.1
3,439,016	-				+0.1
3,439,016	-				+1.4
3,439,235	+		Rv3076	0.34	-0.0
3,439,692	-				-0.4
3,439,692	-				-0.7
3,439,847	-		Rv3077	0.17	-0.1
3,439,880	+		Rv3077	0.19	-0.8