Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv2836c

Experiment: 7H9 with Levofloxacin 0.3 ug/mL

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv2834c and Rv2835c overlap by 4 nucleotidesRv2835c and Rv2836c are separated by 86 nucleotidesRv2836c and Rv2837c are separated by 6 nucleotides Rv2834c: Rv2834c - Probable Sn-glycerol-3-phosphate transport integral membrane protein ABC transporter UgpE, at 3,140,487 to 3,141,314 Rv2834c Rv2835c: Rv2835c - Probable Sn-glycerol-3-phosphate transport integral membrane protein ABC transporter UgpA, at 3,141,311 to 3,142,222 Rv2835c Rv2836c: Rv2836c - Possible DNA-damage-inducible protein F DinF, at 3,142,309 to 3,143,628 Rv2836c Rv2837c: Rv2837c - Conserved protein, at 3,143,635 to 3,144,645 Rv2837c Rv2838c: Rv2838c - Probable ribosome-binding factor a RbfA (P15B protein), at 3,144,620 to 3,145,171 Rv2838c Position (kb) 3142 3143 3144Strain fitness (log2 ratio) -1 0 1 2 3at 3141.435 kb on + strand, within Rv2835cat 3141.435 kb on + strand, within Rv2835cat 3141.436 kb on - strand, within Rv2835cat 3142.023 kb on + strand, within Rv2835cat 3142.128 kb on - strand, within Rv2835cat 3142.233 kb on + strandat 3142.234 kb on - strandat 3143.084 kb on + strand, within Rv2836cat 3143.356 kb on + strand, within Rv2836cat 3143.357 kb on - strand, within Rv2836cat 3143.540 kb on + strandat 3143.540 kb on + strand

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Levofloxacin 0.3 ug/mL
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3,141,435 + Rv2835c 0.14 -0.3
3,141,435 + Rv2835c 0.14 -0.6
3,141,436 - Rv2835c 0.14 -0.0
3,142,023 + Rv2835c 0.78 +0.9
3,142,128 - Rv2835c 0.90 -0.7
3,142,233 + -0.5
3,142,234 - -0.6
3,143,084 + Rv2836c 0.59 +0.7
3,143,356 + Rv2836c 0.79 -0.8
3,143,357 - Rv2836c 0.79 -0.9
3,143,540 + +3.2
3,143,540 + +1.2

Or see this region's nucleotide sequence