Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv2818c

Experiment: 7H9 with Levofloxacin 0.3 ug/mL

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv2817c and Rv2818c are separated by 12 nucleotidesRv2818c and Rv2819c are separated by 95 nucleotides Rv2817c: Rv2817c - Conserved hypothetical protein, at 3,123,967 to 3,124,983 Rv2817c Rv2818c: Rv2818c - Hypothetical protein, at 3,124,996 to 3,126,144 Rv2818c Rv2819c: Rv2819c - Hypothetical protein, at 3,126,240 to 3,127,367 Rv2819c Position (kb) 3124 3125 3126 3127Strain fitness (log2 ratio) -2 -1 0 1at 3124.247 kb on - strand, within Rv2817cat 3124.276 kb on + strand, within Rv2817cat 3124.385 kb on + strand, within Rv2817cat 3124.970 kb on + strandat 3124.971 kb on - strandat 3125.051 kb on + strandat 3125.052 kb on - strandat 3125.372 kb on + strand, within Rv2818cat 3125.419 kb on - strand, within Rv2818cat 3125.663 kb on + strand, within Rv2818cat 3126.038 kb on + strandat 3126.038 kb on + strandat 3126.038 kb on + strandat 3126.038 kb on + strandat 3126.038 kb on + strandat 3126.039 kb on - strandat 3126.151 kb on + strandat 3126.151 kb on + strandat 3126.151 kb on + strandat 3126.284 kb on - strandat 3126.289 kb on - strandat 3126.289 kb on - strandat 3126.289 kb on - strandat 3126.363 kb on + strand, within Rv2819cat 3126.471 kb on + strand, within Rv2819cat 3126.490 kb on + strand, within Rv2819cat 3126.923 kb on - strand, within Rv2819cat 3127.014 kb on - strand, within Rv2819cat 3127.103 kb on + strand, within Rv2819cat 3127.104 kb on - strand, within Rv2819c

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Levofloxacin 0.3 ug/mL
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3,124,247 - Rv2817c 0.28 -1.5
3,124,276 + Rv2817c 0.30 +0.2
3,124,385 + Rv2817c 0.41 -0.1
3,124,970 + -1.2
3,124,971 - -0.6
3,125,051 + +1.7
3,125,052 - -0.8
3,125,372 + Rv2818c 0.33 +0.2
3,125,419 - Rv2818c 0.37 -1.5
3,125,663 + Rv2818c 0.58 -1.0
3,126,038 + -1.3
3,126,038 + +0.5
3,126,038 + +0.6
3,126,038 + -0.8
3,126,038 + -0.9
3,126,039 - -1.1
3,126,151 + +0.0
3,126,151 + -1.0
3,126,151 + -0.3
3,126,284 - -0.2
3,126,289 - -1.7
3,126,289 - -0.3
3,126,289 - -0.3
3,126,363 + Rv2819c 0.11 -2.0
3,126,471 + Rv2819c 0.20 -2.2
3,126,490 + Rv2819c 0.22 -0.5
3,126,923 - Rv2819c 0.61 +0.1
3,127,014 - Rv2819c 0.69 -0.1
3,127,103 + Rv2819c 0.77 +0.5
3,127,104 - Rv2819c 0.77 -1.7

Or see this region's nucleotide sequence