Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv2503c

Experiment: 7H9 with Levofloxacin 0.3 ug/mL

Add experiment(s):

Zoom: Pan:

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

download SVG
500 ntRv2502c and Rv2503c overlap by 4 nucleotidesRv2503c and Rv2504c overlap by 4 nucleotidesRv2504c and Rv2505c are separated by 82 nucleotides Rv2502c: Rv2502c - Probable acetyl-/propionyl-CoA carboxylase (beta subunit) AccD1, at 2,816,885 to 2,818,474 Rv2502c Rv2503c: Rv2503c - Probable succinyl-CoA:3-ketoacid-coenzyme A transferase (beta subunit) ScoB (3-oxo-acid:CoA transferase) (OXCT B) (succinyl CoA:3-oxoacid CoA-transferase), at 2,818,471 to 2,819,127 Rv2503c Rv2504c: Rv2504c - Probable succinyl-CoA:3-ketoacid-coenzyme A transferase (alpha subunit) ScoA (3-oxo acid:CoA transferase) (OXCT A) (succinyl-CoA:3-oxoacid-coenzyme A transferase), at 2,819,124 to 2,819,870 Rv2504c Rv2505c: Rv2505c - Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase), at 2,819,953 to 2,821,596 Rv2505c Position (kb) 2818 2819 2820Strain fitness (log2 ratio) -2 -1 0 1 2at 2817.913 kb on - strand, within Rv2502cat 2818.071 kb on + strand, within Rv2502cat 2818.087 kb on + strand, within Rv2502cat 2818.143 kb on + strand, within Rv2502cat 2818.144 kb on - strand, within Rv2502cat 2818.144 kb on - strand, within Rv2502cat 2818.248 kb on + strand, within Rv2502cat 2818.400 kb on - strandat 2818.400 kb on - strandat 2818.451 kb on + strandat 2818.523 kb on - strandat 2818.655 kb on - strand, within Rv2503cat 2818.781 kb on - strand, within Rv2503cat 2819.057 kb on + strand, within Rv2503cat 2819.058 kb on - strand, within Rv2503cat 2819.208 kb on + strand, within Rv2504cat 2819.318 kb on - strand, within Rv2504cat 2819.395 kb on + strand, within Rv2504cat 2819.396 kb on - strand, within Rv2504cat 2819.518 kb on + strand, within Rv2504cat 2819.519 kb on - strand, within Rv2504cat 2819.827 kb on - strandat 2819.923 kb on - strandat 2819.946 kb on - strandat 2819.946 kb on - strandat 2820.008 kb on - strandat 2820.092 kb on + strandat 2820.092 kb on + strand

download strain data

Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Levofloxacin 0.3 ug/mL
remove
2,817,913 - Rv2502c 0.65 -1.0
2,818,071 + Rv2502c 0.75 +1.2
2,818,087 + Rv2502c 0.76 -1.0
2,818,143 + Rv2502c 0.79 -0.7
2,818,144 - Rv2502c 0.79 -0.2
2,818,144 - Rv2502c 0.79 -0.6
2,818,248 + Rv2502c 0.86 -0.9
2,818,400 - -1.4
2,818,400 - -0.6
2,818,451 + +2.2
2,818,523 - +0.0
2,818,655 - Rv2503c 0.28 -2.2
2,818,781 - Rv2503c 0.47 -1.4
2,819,057 + Rv2503c 0.89 -2.3
2,819,058 - Rv2503c 0.89 -1.1
2,819,208 + Rv2504c 0.11 +0.1
2,819,318 - Rv2504c 0.26 +1.1
2,819,395 + Rv2504c 0.36 -1.0
2,819,396 - Rv2504c 0.36 -0.2
2,819,518 + Rv2504c 0.53 -0.2
2,819,519 - Rv2504c 0.53 -1.9
2,819,827 - -0.3
2,819,923 - -1.3
2,819,946 - -0.9
2,819,946 - -0.4
2,820,008 - -1.8
2,820,092 + -0.7
2,820,092 + -1.3

Or see this region's nucleotide sequence