Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv2496c

Experiment: 7H9 with Levofloxacin 0.3 ug/mL

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv2495c and Rv2496c overlap by 4 nucleotidesRv2496c and Rv2497c are separated by 10 nucleotides Rv2495c: Rv2495c - Probable branched-chain keto acid dehydrogenase E2 component BkdC, at 2,808,758 to 2,809,939 Rv2495c Rv2496c: Rv2496c - Probable branched-chain keto acid dehydrogenase E1 component, beta subunit BkdB, at 2,809,936 to 2,810,982 Rv2496c Rv2497c: Rv2497c - Probable branched-chain keto acid dehydrogenase E1 component, alpha subunit BkdA, at 2,810,993 to 2,812,096 Rv2497c Position (kb) 2809 2810 2811Strain fitness (log2 ratio) -3 -2 -1 0 1 2 3at 2810.253 kb on + strand, within Rv2496cat 2810.408 kb on + strand, within Rv2496cat 2810.510 kb on + strand, within Rv2496cat 2810.510 kb on + strand, within Rv2496cat 2810.550 kb on + strand, within Rv2496cat 2810.701 kb on + strand, within Rv2496cat 2810.701 kb on + strand, within Rv2496cat 2810.779 kb on - strand, within Rv2496cat 2810.874 kb on - strand, within Rv2496cat 2811.063 kb on + strandat 2811.122 kb on + strand, within Rv2497cat 2811.198 kb on - strand, within Rv2497cat 2811.198 kb on - strand, within Rv2497cat 2811.202 kb on - strand, within Rv2497cat 2811.306 kb on + strand, within Rv2497cat 2811.379 kb on - strand, within Rv2497cat 2811.511 kb on - strand, within Rv2497cat 2811.561 kb on - strand, within Rv2497cat 2811.561 kb on - strand, within Rv2497cat 2811.776 kb on + strand, within Rv2497cat 2811.827 kb on + strand, within Rv2497cat 2811.828 kb on - strand, within Rv2497cat 2811.879 kb on + strand, within Rv2497cat 2811.880 kb on - strand, within Rv2497cat 2811.954 kb on + strand, within Rv2497c

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Levofloxacin 0.3 ug/mL
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2,810,253 + Rv2496c 0.30 -0.3
2,810,408 + Rv2496c 0.45 -1.6
2,810,510 + Rv2496c 0.55 -1.5
2,810,510 + Rv2496c 0.55 +2.2
2,810,550 + Rv2496c 0.59 -2.2
2,810,701 + Rv2496c 0.73 -1.2
2,810,701 + Rv2496c 0.73 +3.2
2,810,779 - Rv2496c 0.81 -1.4
2,810,874 - Rv2496c 0.90 -0.3
2,811,063 + +0.2
2,811,122 + Rv2497c 0.12 -1.2
2,811,198 - Rv2497c 0.19 -0.2
2,811,198 - Rv2497c 0.19 -0.7
2,811,202 - Rv2497c 0.19 -0.3
2,811,306 + Rv2497c 0.28 -0.4
2,811,379 - Rv2497c 0.35 -0.2
2,811,511 - Rv2497c 0.47 -1.1
2,811,561 - Rv2497c 0.51 +1.5
2,811,561 - Rv2497c 0.51 -0.1
2,811,776 + Rv2497c 0.71 -0.5
2,811,827 + Rv2497c 0.76 +3.2
2,811,828 - Rv2497c 0.76 -3.0
2,811,879 + Rv2497c 0.80 +1.7
2,811,880 - Rv2497c 0.80 +1.5
2,811,954 + Rv2497c 0.87 +2.6

Or see this region's nucleotide sequence