Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv2481c

Experiment: 7H9 with Levofloxacin 0.3 ug/mL

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

Per-strain Table

Position	Strand	Gene	LocusTag	Fraction	7H9 with Levofloxacin 0.3 ug/mL
2,786,004	+				-0.9
2,786,060	+				-0.7
2,786,073	-				-0.6
2,786,155	-				+0.7
2,786,163	-				-0.4
2,786,163	-				-0.8
2,786,214	+				-0.6
2,786,215	-				-0.1
2,786,292	+				-0.6
2,786,293	-				-1.7
2,786,359	+				-0.8
2,786,381	-				-2.5
2,786,385	-				-0.5
2,786,394	+				-0.8
2,786,394	+				-0.1
2,786,452	+				+0.1
2,786,452	+				+1.0
2,786,453	-				-1.2
2,786,453	-				-1.5
2,786,453	-				-0.9
2,786,576	+				-0.3
2,786,576	+				-0.5
2,786,576	+				+0.2
2,786,577	-				+0.6
2,786,584	+				-0.6
2,786,584	+				+1.2
2,786,585	-				-2.6
2,786,587	-				-0.3
2,786,602	-				+0.8
2,786,725	+		Rv2481c	0.46	-0.2
2,786,726	-		Rv2481c	0.47	-0.2
2,786,726	-		Rv2481c	0.47	+0.7
2,786,886	+				+0.2
2,786,915	+				-0.8
2,786,916	-				+0.1
2,787,014	-				+2.2
2,787,037	-				+1.2
2,787,037	-				-0.3
2,787,037	-				-0.5
2,787,037	-				+0.7
2,787,245	+		Rv2482c	0.14	-0.3
2,787,246	-		Rv2482c	0.14	+0.7
2,787,246	-		Rv2482c	0.14	+1.2
2,787,300	-		Rv2482c	0.16	-0.5
2,787,410	+		Rv2482c	0.21	-0.1
2,787,410	+		Rv2482c	0.21	+3.2
2,787,410	+		Rv2482c	0.21	+1.7
2,787,411	-		Rv2482c	0.21	-0.5
2,787,411	-		Rv2482c	0.21	-0.0
2,787,555	-		Rv2482c	0.27	+1.1
2,787,587	-		Rv2482c	0.28	-1.2
2,787,587	-		Rv2482c	0.28	-0.5
2,787,590	+		Rv2482c	0.29	-2.0
2,787,591	-		Rv2482c	0.29	+1.2