Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv2444c

Experiment: 7H9 with Levofloxacin 0.3 ug/mL

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

Per-strain Table

Position	Strand	Gene	LocusTag	Fraction	7H9 with Levofloxacin 0.3 ug/mL
2,741,375	-		Rv2443	0.45	+1.3
2,741,436	-		Rv2443	0.49	-1.9
2,741,478	+		Rv2443	0.52	-0.2
2,741,478	+		Rv2443	0.52	+0.4
2,741,479	-		Rv2443	0.52	-1.3
2,741,522	+		Rv2443	0.55	+1.7
2,741,526	+		Rv2443	0.55	-0.6
2,741,537	+		Rv2443	0.56	-2.3
2,741,538	-		Rv2443	0.56	+0.4
2,741,677	+		Rv2443	0.66	-0.5
2,741,677	+		Rv2443	0.66	-0.5
2,741,677	+		Rv2443	0.66	+1.3
2,741,678	-		Rv2443	0.66	+0.5
2,741,681	+		Rv2443	0.66	-0.4
2,741,682	-		Rv2443	0.66	-1.2
2,742,602	+		Rv2444c	0.17	-2.2
2,742,602	+		Rv2444c	0.17	-1.7
2,742,602	+		Rv2444c	0.17	-1.8
2,742,602	+		Rv2444c	0.17	+0.7
2,742,603	-		Rv2444c	0.17	+3.3
2,742,603	-		Rv2444c	0.17	-2.1
2,744,980	-				-0.7
2,744,980	-				+0.1
2,745,044	-				-0.7
2,745,737	+				+3.3
2,745,737	+				-0.1
2,745,737	+				-0.5
2,745,737	+				-0.9
2,745,737	+				-0.4
2,745,737	+				+2.9
2,745,738	-				+2.3
2,745,738	-				-0.2
2,745,753	+				+0.3
2,745,753	+				+0.0
2,745,753	+				+0.5
2,745,753	+				-1.8
2,745,754	-				-1.0
2,745,754	-				+0.5
2,745,754	-				+0.2
2,745,816	+		Rv2446c	0.13	-1.4
2,745,816	+		Rv2446c	0.13	-0.0
2,745,817	-		Rv2446c	0.13	-0.5
2,745,960	-		Rv2446c	0.52	+1.5
2,745,960	-		Rv2446c	0.52	-0.8
2,745,960	-		Rv2446c	0.52	-1.4