Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv2374c

Experiment: 7H9 with Levofloxacin 0.3 ug/mL

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

Per-strain Table

Position	Strand	Gene	LocusTag	Fraction	7H9 with Levofloxacin 0.3 ug/mL
2,654,001	-				-0.0
2,654,091	-				-0.3
2,654,161	-				+0.3
2,654,368	+		Rv2374c	0.30	-1.0
2,654,432	-		Rv2374c	0.36	-1.8
2,654,927	+		Rv2374c	0.84	+1.0
2,654,927	+		Rv2374c	0.84	+1.3
2,654,928	-		Rv2374c	0.84	-1.9
2,654,928	-		Rv2374c	0.84	+1.3
2,654,989	-		Rv2374c	0.90	+0.3
2,655,114	+				+2.0
2,655,115	-				+0.0
2,655,115	-				+0.1
2,655,115	-				+0.3
2,655,167	+				-0.7
2,655,167	+				-0.1
2,655,167	+				-2.0
2,655,167	+				+0.0
2,655,167	+				-0.6
2,655,168	-				-1.6
2,655,209	-				+0.5
2,655,319	+		Rv2375	0.17	-0.5
2,655,319	+		Rv2375	0.17	-2.7
2,655,319	+		Rv2375	0.17	-0.7
2,655,320	-		Rv2375	0.17	-0.9
2,655,320	-		Rv2375	0.17	-1.1
2,655,321	+		Rv2375	0.18	-0.9
2,655,322	-		Rv2375	0.18	-0.8
2,655,381	+		Rv2375	0.36	-0.8
2,655,428	-		Rv2375	0.51	-0.5
2,655,472	+		Rv2375	0.65	-0.7
2,655,472	+		Rv2375	0.65	-0.0
2,655,472	+		Rv2375	0.65	-0.5
2,655,531	-		Rv2375	0.84	-0.3
2,655,531	-		Rv2375	0.84	-0.4
2,656,014	+		Rv2376c	0.80	+0.3
2,656,015	-		Rv2376c	0.80	-0.9