Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv2230c

Experiment: 7H9 with Levofloxacin 0.3 ug/mL

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv2228c and Rv2229c overlap by 4 nucleotidesRv2229c and Rv2230c overlap by 4 nucleotidesRv2230c and Rv2231c overlap by 4 nucleotides Rv2228c: Rv2228c - Multifunctional protein. Has RNASE H,alpha-ribazole phosphatase, and acid phosphatase activities., at 2,501,644 to 2,502,738 Rv2228c Rv2229c: Rv2229c - Conserved protein, at 2,502,735 to 2,503,472 Rv2229c Rv2230c: Rv2230c - Conserved protein, at 2,503,469 to 2,504,608 Rv2230c Rv2231c: Rv2231c - Possible aminotransferase CobC, at 2,504,605 to 2,505,699 Rv2231c Position (kb) 2503 2504 2505Strain fitness (log2 ratio) -3 -2 -1 0 1at 2503.441 kb on - strandat 2504.191 kb on - strand, within Rv2230cat 2505.009 kb on - strand, within Rv2231c

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Levofloxacin 0.3 ug/mL
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2,503,441 - -0.1
2,504,191 - Rv2230c 0.63 -2.9
2,505,009 - Rv2231c 0.37 -1.1

Or see this region's nucleotide sequence