Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv2222c

Experiment: 7H9 with Levofloxacin 0.3 ug/mL

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

Per-strain Table

Position	Strand	Gene	LocusTag	Fraction	7H9 with Levofloxacin 0.3 ug/mL
2,491,881	-		Rv2221c	0.84	-0.5
2,492,404	-				+5.8
2,492,416	-				+2.3
2,492,416	-				-0.2
2,492,451	+				-0.1
2,492,619	-		Rv2222c	0.16	+0.5
2,492,704	-		Rv2222c	0.23	+2.3
2,492,732	+		Rv2222c	0.25	-1.2
2,492,733	-		Rv2222c	0.25	+0.8
2,492,770	-		Rv2222c	0.27	-2.9
2,492,856	+		Rv2222c	0.34	-0.2
2,493,252	-		Rv2222c	0.63	-1.5
2,493,360	+		Rv2222c	0.71	+2.9
2,493,754	+				-0.7
2,493,990	+				+1.2
2,494,003	+		Rv2223c	0.11	-0.2
2,494,149	-		Rv2223c	0.20	+1.3
2,494,149	-		Rv2223c	0.20	-0.7
2,494,149	-		Rv2223c	0.20	+0.1
2,494,291	+		Rv2223c	0.29	-1.0
2,494,291	+		Rv2223c	0.29	+0.3
2,494,292	-		Rv2223c	0.29	-1.0
2,494,292	-		Rv2223c	0.29	+0.5
2,494,292	-		Rv2223c	0.29	-1.2
2,494,384	+		Rv2223c	0.35	-0.4
2,494,385	-		Rv2223c	0.35	+0.5
2,494,420	+		Rv2223c	0.37	-0.1
2,494,420	+		Rv2223c	0.37	-0.6
2,494,421	-		Rv2223c	0.37	-1.0
2,494,487	-		Rv2223c	0.42	+0.8
2,494,555	+		Rv2223c	0.46	-0.5
2,494,555	+		Rv2223c	0.46	+1.3
2,494,556	-		Rv2223c	0.46	-0.2
2,494,629	-		Rv2223c	0.51	-2.5
2,494,662	-		Rv2223c	0.53	+1.0
2,494,703	-		Rv2223c	0.55	+1.2
2,494,703	-		Rv2223c	0.55	-0.0
2,494,703	-		Rv2223c	0.55	+0.6
2,494,717	+		Rv2223c	0.56	-1.2
2,494,717	+		Rv2223c	0.56	+0.1
2,494,717	+		Rv2223c	0.56	-0.5