Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv2095c

Experiment: 7H9 with Levofloxacin 0.3 ug/mL

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv2093c and Rv2094c are separated by 16 nucleotidesRv2094c and Rv2095c are separated by 67 nucleotidesRv2095c and Rv2096c overlap by 4 nucleotides Rv2093c: Rv2093c - Sec-independent protein translocase transmembrane protein TatC, at 2,352,103 to 2,353,029 Rv2093c Rv2094c: Rv2094c - Sec-independent protein translocase membrane-bound protein TatA, at 2,353,046 to 2,353,297 Rv2094c Rv2095c: Rv2095c - Proteasome accessory factor C PafC, at 2,353,365 to 2,354,315 Rv2095c Rv2096c: Rv2096c - Proteasome accessory factor B PafB, at 2,354,312 to 2,355,310 Rv2096c Position (kb) 2353 2354 2355Strain fitness (log2 ratio) -3 -2 -1 0 1 2at 2353.329 kb on - strandat 2353.388 kb on - strandat 2353.388 kb on - strandat 2353.388 kb on - strandat 2353.388 kb on - strandat 2353.479 kb on + strand, within Rv2095cat 2353.479 kb on + strand, within Rv2095cat 2353.479 kb on + strand, within Rv2095cat 2353.507 kb on + strand, within Rv2095cat 2353.508 kb on - strand, within Rv2095cat 2353.508 kb on - strand, within Rv2095cat 2353.508 kb on - strand, within Rv2095cat 2353.508 kb on - strand, within Rv2095cat 2353.548 kb on + strand, within Rv2095cat 2353.548 kb on + strand, within Rv2095cat 2353.548 kb on + strand, within Rv2095cat 2353.548 kb on + strand, within Rv2095cat 2353.549 kb on - strand, within Rv2095cat 2353.567 kb on + strand, within Rv2095cat 2353.568 kb on - strand, within Rv2095cat 2353.568 kb on - strand, within Rv2095cat 2353.771 kb on + strand, within Rv2095cat 2353.771 kb on + strand, within Rv2095cat 2353.771 kb on + strand, within Rv2095cat 2353.772 kb on - strand, within Rv2095cat 2353.772 kb on - strand, within Rv2095cat 2353.846 kb on + strand, within Rv2095cat 2353.846 kb on + strand, within Rv2095cat 2354.071 kb on - strand, within Rv2095cat 2354.266 kb on + strandat 2354.266 kb on + strandat 2354.541 kb on - strand, within Rv2096cat 2354.597 kb on + strand, within Rv2096cat 2354.597 kb on + strand, within Rv2096cat 2354.598 kb on - strand, within Rv2096cat 2354.719 kb on - strand, within Rv2096cat 2354.719 kb on - strand, within Rv2096cat 2354.773 kb on - strand, within Rv2096cat 2354.773 kb on - strand, within Rv2096cat 2355.207 kb on + strand, within Rv2096cat 2355.270 kb on - strand

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Levofloxacin 0.3 ug/mL
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2,353,329 - -0.4
2,353,388 - -2.2
2,353,388 - -2.4
2,353,388 - -2.3
2,353,388 - -1.3
2,353,479 + Rv2095c 0.12 -1.7
2,353,479 + Rv2095c 0.12 -2.7
2,353,479 + Rv2095c 0.12 +0.8
2,353,507 + Rv2095c 0.15 -2.0
2,353,508 - Rv2095c 0.15 -3.3
2,353,508 - Rv2095c 0.15 -1.9
2,353,508 - Rv2095c 0.15 -0.5
2,353,508 - Rv2095c 0.15 -1.5
2,353,548 + Rv2095c 0.19 -2.8
2,353,548 + Rv2095c 0.19 -1.8
2,353,548 + Rv2095c 0.19 -3.6
2,353,548 + Rv2095c 0.19 +1.4
2,353,549 - Rv2095c 0.19 -2.2
2,353,567 + Rv2095c 0.21 -2.2
2,353,568 - Rv2095c 0.21 -1.5
2,353,568 - Rv2095c 0.21 -2.3
2,353,771 + Rv2095c 0.43 -3.6
2,353,771 + Rv2095c 0.43 -1.7
2,353,771 + Rv2095c 0.43 -1.2
2,353,772 - Rv2095c 0.43 -2.5
2,353,772 - Rv2095c 0.43 -0.6
2,353,846 + Rv2095c 0.51 -1.8
2,353,846 + Rv2095c 0.51 -1.9
2,354,071 - Rv2095c 0.74 +0.6
2,354,266 + -2.2
2,354,266 + -1.8
2,354,541 - Rv2096c 0.23 -3.4
2,354,597 + Rv2096c 0.29 -1.3
2,354,597 + Rv2096c 0.29 +2.4
2,354,598 - Rv2096c 0.29 -2.1
2,354,719 - Rv2096c 0.41 -0.8
2,354,719 - Rv2096c 0.41 +0.8
2,354,773 - Rv2096c 0.46 +1.4
2,354,773 - Rv2096c 0.46 +0.0
2,355,207 + Rv2096c 0.90 +1.4
2,355,270 - -1.5

Or see this region's nucleotide sequence