Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv1991c

Experiment: 7H9 with Levofloxacin 0.3 ug/mL

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

Per-strain Table

Position	Strand	Gene	LocusTag	Fraction	7H9 with Levofloxacin 0.3 ug/mL
2,233,677	-				+0.8
2,233,680	-				+0.7
2,233,874	+				+2.4
2,233,882	+				+0.1
2,233,962	+		Rv1990A	0.24	+0.4
2,233,963	-		Rv1990A	0.24	+0.6
2,234,070	+		Rv1990A	0.56	-0.9
2,234,070	+		Rv1990A	0.56	+1.1
2,234,070	+		Rv1990A	0.56	-0.4
2,234,070	+		Rv1990A	0.56	+0.1
2,234,071	-		Rv1990A	0.57	-0.7
2,234,071	-		Rv1990A	0.57	+2.0
2,234,183	+				-1.2
2,234,235	+				+0.6
2,234,258	-				-0.6
2,234,258	-				-1.3
2,234,318	-				-0.2
2,234,496	+		Rv1991c	0.55	-1.3
2,234,497	-		Rv1991c	0.56	+0.1
2,234,497	-		Rv1991c	0.56	+0.3
2,234,497	-		Rv1991c	0.56	-0.4
2,234,497	-		Rv1991c	0.56	-0.6
2,234,546	+		Rv1991c	0.70	-1.3
2,234,546	+		Rv1991c	0.70	+0.4
2,234,563	+		Rv1991c	0.75	-0.7
2,234,564	-		Rv1991c	0.75	-1.7
2,234,564	-		Rv1991c	0.75	-2.9
2,234,625	-				+1.4
2,234,625	-				-1.1
2,234,640	+				+0.3
2,234,640	+				-0.2
2,234,641	-				-0.7
2,234,641	-				+2.4
2,234,641	-				+3.1
2,234,880	-				-0.1
2,234,880	-				+0.5
2,234,880	-				-0.8
2,234,880	-				+2.4
2,235,161	+				-0.8
2,235,161	+				-0.4
2,235,162	-				+0.3
2,235,162	-				+2.1
2,235,162	-				-0.7
2,235,162	-				-1.2
2,235,162	-				+0.8
2,235,162	-				+2.4
2,235,162	-				+0.4
2,235,162	-				-0.9
2,235,165	+				-2.1
2,235,166	-				+0.8
2,235,166	-				+0.1
2,235,220	-				+0.5
2,235,220	-				-2.1
2,235,435	+		Rv1992c	0.19	+0.3
2,235,435	+		Rv1992c	0.19	+0.5
2,235,435	+		Rv1992c	0.19	+0.1
2,235,435	+		Rv1992c	0.19	-0.7
2,235,435	+		Rv1992c	0.19	+0.9
2,235,558	+		Rv1992c	0.24	-1.2
2,235,558	+		Rv1992c	0.24	-0.9
2,235,559	-		Rv1992c	0.25	-0.2
2,235,559	-		Rv1992c	0.25	-0.7