Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv1963c

Experiment: 7H9 with Levofloxacin 0.3 ug/mL

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

Per-strain Table

Position	Strand	Gene	LocusTag	Fraction	7H9 with Levofloxacin 0.3 ug/mL
2,204,638	+		Rv1961	0.86	-0.7
2,204,728	+				-0.4
2,204,783	-				+1.1
2,204,787	+				-0.8
2,204,923	-		Rv1962c	0.14	-0.6
2,204,936	+		Rv1962c	0.17	+0.9
2,204,937	-		Rv1962c	0.17	-2.7
2,204,989	+		Rv1962c	0.30	-0.2
2,204,989	+		Rv1962c	0.30	+1.1
2,204,995	+		Rv1962c	0.32	+3.7
2,205,049	+		Rv1962c	0.45	+0.8
2,205,143	-		Rv1962c	0.68	-0.8
2,205,143	-		Rv1962c	0.68	-0.5
2,205,143	-		Rv1962c	0.68	-0.3
2,205,208	+		Rv1962c	0.84	-0.1
2,205,238	+				-0.4
2,205,267	-				-0.2
2,205,281	+				-0.5
2,205,437	-		Rv1962A	0.59	-1.8
2,205,599	+				-0.1
2,205,599	+				-0.9
2,205,599	+				-0.4
2,205,600	-				+0.1
2,206,585	+		Rv1963c	0.82	-0.9
2,206,585	+		Rv1963c	0.82	-0.9
2,206,640	-		Rv1963c	0.87	+0.1
2,206,847	-				+1.4
2,207,019	+				-2.2
2,207,253	-				+1.6
2,207,253	-				-0.3
2,207,263	+				-0.9
2,207,704	+				-1.2
2,207,704	+				-0.0
2,207,705	-				+0.6