Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv1900c

Experiment: 7H9 with Levofloxacin 0.3 ug/mL

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

Per-strain Table

Position	Strand	Gene	LocusTag	Fraction	7H9 with Levofloxacin 0.3 ug/mL
2,145,246	+				-0.5
2,145,247	-				-0.6
2,145,247	-				-0.4
2,145,292	+				-1.2
2,145,292	+				+0.2
2,145,293	-				-1.3
2,145,293	-				-0.8
2,145,487	+		Rv1899c	0.26	+0.3
2,145,487	+		Rv1899c	0.26	+0.9
2,145,488	-		Rv1899c	0.27	-0.1
2,145,488	-		Rv1899c	0.27	-0.2
2,145,712	+		Rv1899c	0.48	-1.5
2,145,712	+		Rv1899c	0.48	+1.1
2,145,713	-		Rv1899c	0.48	+0.8
2,145,713	-		Rv1899c	0.48	+0.4
2,145,713	-		Rv1899c	0.48	+3.0
2,145,713	-		Rv1899c	0.48	-0.9
2,145,753	+		Rv1899c	0.52	+1.6
2,145,754	-		Rv1899c	0.52	+0.3
2,145,883	-		Rv1899c	0.65	+0.9
2,145,951	+		Rv1899c	0.71	+0.9
2,145,952	-		Rv1899c	0.72	-1.4
2,146,515	-		Rv1900c	0.19	+1.4
2,146,922	-		Rv1900c	0.49	-0.9
2,146,922	-		Rv1900c	0.49	+0.2
2,146,922	-		Rv1900c	0.49	+0.3
2,146,922	-		Rv1900c	0.49	-1.3
2,147,094	-		Rv1900c	0.61	+0.8
2,147,197	+		Rv1900c	0.69	-0.9
2,147,212	-		Rv1900c	0.70	+2.4
2,147,479	+		Rv1900c	0.89	+2.4
2,147,639	+				-0.7
2,147,639	+				+0.0
2,147,640	-				-0.3
2,147,644	+				-0.4
2,147,644	+				+0.3
2,147,644	+				+0.0
2,147,644	+				-0.3
2,147,645	-				-0.1
2,147,645	-				-0.7
2,147,645	-				-0.7
2,147,645	-				+0.2
2,147,655	+				+1.2
2,147,656	-				-1.0
2,147,656	-				-0.1
2,147,901	+		Rv1901	0.18	+0.3
2,147,902	-		Rv1901	0.19	-0.4
2,147,926	+		Rv1901	0.20	+2.1
2,147,926	+		Rv1901	0.20	+0.9
2,147,926	+		Rv1901	0.20	-0.4
2,148,038	+		Rv1901	0.29	-0.7
2,148,238	+		Rv1901	0.45	-0.9
2,148,238	+		Rv1901	0.45	-0.3
2,148,239	-		Rv1901	0.45	-0.8
2,148,239	-		Rv1901	0.45	+1.1
2,148,333	-		Rv1901	0.52	-0.4
2,148,409	+		Rv1901	0.58	-0.3
2,148,503	+		Rv1901	0.65	+0.4
2,148,504	-		Rv1901	0.65	+1.4
2,148,589	+		Rv1901	0.72	-0.7
2,148,613	+		Rv1901	0.74	+0.8
2,148,614	-		Rv1901	0.74	-0.0
2,148,618	+		Rv1901	0.74	-0.6
2,148,618	+		Rv1901	0.74	+1.7