Experiment: 7H9 with Levofloxacin 0.3 ug/mL
Only strains with sufficient reads to estimate fitness are shown,
but the strain fitness values are still rather noisy and may be biased towards zero.
Strains near the edge of a gene are not shown as being associated with that
gene (they are in grey).
Strains in the central 10-90% of a gene are color coded by the insertion's strand.
Usually, "+" means that the selectable marker is encoded on the forward strand,
i.e., transcribed rightward.
500 nt Rv1822 and Rv1823 overlap by 8 nucleotides Rv1823 and Rv1824 are separated by 28 nucleotides Rv1824 and Rv1825 are separated by 16 nucleotides Rv1825 and Rv1826 are separated by 37 nucleotides
Rv1822: Rv1822 - Probable CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase PgsA2 (PGP synthase) (phosphatidylglycerophosphate synthase) (3-phosphatidyl-1'-glycerol-3'phosphate synthase), at 2,069,080 to 2,069,709
Rv1822
Rv1823: Rv1823 - Conserved protein, at 2,069,702 to 2,070,625
Rv1823
Rv1824: Rv1824 - Conserved hypothetical membrane protein, at 2,070,654 to 2,071,019
Rv1824
Rv1825: Rv1825 - Conserved protein, at 2,071,036 to 2,071,914
Rv1825
Rv1826: Rv1826 - Probable glycine cleavage system H protein GcvH, at 2,071,952 to 2,072,356
Rv1826
Position (kb)
2070
2071
2072 Strain fitness (log2 ratio)
-3
-2
-1
0
1
2 at 2069.814 kb on + strand, within Rv1823 at 2070.160 kb on + strand, within Rv1823 at 2070.161 kb on - strand, within Rv1823 at 2070.430 kb on + strand, within Rv1823 at 2070.438 kb on - strand, within Rv1823 at 2070.530 kb on + strand, within Rv1823 at 2070.531 kb on - strand, within Rv1823 at 2070.623 kb on + strand at 2070.645 kb on + strand at 2070.769 kb on - strand, within Rv1824 at 2070.769 kb on - strand, within Rv1824 at 2071.287 kb on - strand, within Rv1825 at 2071.349 kb on + strand, within Rv1825 at 2071.350 kb on - strand, within Rv1825 at 2071.350 kb on - strand, within Rv1825 at 2071.350 kb on - strand, within Rv1825 at 2071.466 kb on + strand, within Rv1825 at 2071.483 kb on - strand, within Rv1825 at 2071.483 kb on - strand, within Rv1825 at 2071.545 kb on - strand, within Rv1825 at 2071.571 kb on + strand, within Rv1825 at 2071.894 kb on + strand at 2071.894 kb on + strand at 2071.894 kb on + strand
Per-strain Table
Position Strand Gene LocusTag Fraction 7H9 with Levofloxacin 0.3 ug/mL remove 2,069,814 + Rv1823 0.12 +0.4 2,070,160 + Rv1823 0.50 -0.8 2,070,161 - Rv1823 0.50 -0.7 2,070,430 + Rv1823 0.79 -0.6 2,070,438 - Rv1823 0.80 -1.4 2,070,530 + Rv1823 0.90 -1.6 2,070,531 - Rv1823 0.90 +2.4 2,070,623 + -1.6 2,070,645 + -0.9 2,070,769 - Rv1824 0.31 -1.3 2,070,769 - Rv1824 0.31 -3.2 2,071,287 - Rv1825 0.29 +2.4 2,071,349 + Rv1825 0.36 -0.3 2,071,350 - Rv1825 0.36 -0.4 2,071,350 - Rv1825 0.36 +0.7 2,071,350 - Rv1825 0.36 +1.4 2,071,466 + Rv1825 0.49 -1.7 2,071,483 - Rv1825 0.51 +0.1 2,071,483 - Rv1825 0.51 +0.1 2,071,545 - Rv1825 0.58 -1.5 2,071,571 + Rv1825 0.61 -1.7 2,071,894 + -0.1 2,071,894 + -0.7 2,071,894 + -1.3
Or see this region's nucleotide sequence