Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv1671

Experiment: 7H9 with Levofloxacin 0.3 ug/mL

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv1669 and Rv1670 are separated by 32 nucleotidesRv1670 and Rv1671 are separated by 7 nucleotidesRv1671 and Rv1672c are separated by 8 nucleotides Rv1669: Rv1669 - Hypothetical protein, at 1,895,725 to 1,896,087 Rv1669 Rv1670: Rv1670 - Conserved hypothetical protein, at 1,896,120 to 1,896,467 Rv1670 Rv1671: Rv1671 - Probable membrane protein, at 1,896,475 to 1,896,867 Rv1671 Rv1672c: Rv1672c - Probable conserved integral membrane transport protein, at 1,896,876 to 1,898,207 Rv1672c Position (kb) 1896 1897Strain fitness (log2 ratio) -3 -2 -1 0 1 2at 1895.652 kb on - strandat 1895.876 kb on + strand, within Rv1669at 1895.877 kb on - strand, within Rv1669at 1895.891 kb on + strand, within Rv1669at 1895.960 kb on + strand, within Rv1669at 1895.961 kb on - strand, within Rv1669at 1896.005 kb on - strand, within Rv1669at 1896.280 kb on - strand, within Rv1670at 1896.280 kb on - strand, within Rv1670at 1896.303 kb on + strand, within Rv1670at 1896.334 kb on - strand, within Rv1670at 1896.334 kb on - strand, within Rv1670at 1896.336 kb on + strand, within Rv1670at 1896.628 kb on - strand, within Rv1671at 1896.673 kb on + strand, within Rv1671at 1896.674 kb on - strand, within Rv1671at 1896.821 kb on - strand, within Rv1671at 1896.866 kb on - strandat 1896.874 kb on + strandat 1896.933 kb on + strandat 1896.934 kb on - strandat 1896.988 kb on - strandat 1897.281 kb on - strand, within Rv1672cat 1897.354 kb on + strand, within Rv1672cat 1897.416 kb on + strand, within Rv1672cat 1897.444 kb on + strand, within Rv1672cat 1897.456 kb on + strand, within Rv1672cat 1897.468 kb on + strand, within Rv1672c

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Levofloxacin 0.3 ug/mL
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1,895,652 - +0.1
1,895,876 + Rv1669 0.42 -0.9
1,895,877 - Rv1669 0.42 -0.4
1,895,891 + Rv1669 0.46 -1.8
1,895,960 + Rv1669 0.65 -0.4
1,895,961 - Rv1669 0.65 -2.2
1,896,005 - Rv1669 0.77 +0.1
1,896,280 - Rv1670 0.46 +0.8
1,896,280 - Rv1670 0.46 -1.3
1,896,303 + Rv1670 0.53 +0.7
1,896,334 - Rv1670 0.61 -0.1
1,896,334 - Rv1670 0.61 -0.1
1,896,336 + Rv1670 0.62 +0.1
1,896,628 - Rv1671 0.39 -0.3
1,896,673 + Rv1671 0.50 -1.3
1,896,674 - Rv1671 0.51 -0.9
1,896,821 - Rv1671 0.88 -0.7
1,896,866 - -0.7
1,896,874 + +0.2
1,896,933 + +0.3
1,896,934 - -0.6
1,896,988 - +0.8
1,897,281 - Rv1672c 0.30 -1.6
1,897,354 + Rv1672c 0.36 -3.0
1,897,416 + Rv1672c 0.41 -0.3
1,897,444 + Rv1672c 0.43 +2.4
1,897,456 + Rv1672c 0.44 +0.1
1,897,468 + Rv1672c 0.44 +2.4

Or see this region's nucleotide sequence