Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv1232c

Experiment: 7H9 with Levofloxacin 0.3 ug/mL

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

Per-strain Table

Position	Strand	Gene	LocusTag	Fraction	7H9 with Levofloxacin 0.3 ug/mL
1,373,915	+		Rv1230c	0.77	+0.4
1,373,916	-		Rv1230c	0.77	-0.5
1,373,916	-		Rv1230c	0.77	-1.3
1,373,983	-		Rv1230c	0.83	-0.8
1,374,232	+				-1.0
1,374,233	-				+2.3
1,374,233	-				-0.8
1,374,233	-				+0.7
1,374,243	-				+0.6
1,374,267	+				+1.5
1,374,267	+				-1.0
1,374,278	-				-0.0
1,374,444	-		Rv1231c	0.22	-0.1
1,374,503	+		Rv1231c	0.33	-0.5
1,374,503	+		Rv1231c	0.33	+2.3
1,374,503	+		Rv1231c	0.33	+2.1
1,374,504	-		Rv1231c	0.34	-1.0
1,374,611	+		Rv1231c	0.53	-1.9
1,374,709	+		Rv1231c	0.71	+0.5
1,374,709	+		Rv1231c	0.71	-2.4
1,374,734	+		Rv1231c	0.76	-0.6
1,374,833	+				-1.8
1,374,833	+				-0.2
1,374,914	+				+0.2
1,374,914	+				-0.4
1,374,939	+				-0.7
1,374,939	+				+0.1
1,374,939	+				-0.6
1,374,939	+				+1.3
1,374,939	+				+0.3
1,374,939	+				+4.6
1,374,940	-				-0.3
1,375,033	+		Rv1232c	0.13	-0.3
1,375,764	-		Rv1232c	0.69	-1.0
1,375,998	+		Rv1232c	0.87	-0.9
1,375,999	-		Rv1232c	0.87	-0.9
1,376,146	+				-0.5
1,376,146	+				+0.9
1,376,147	-				-0.8
1,376,147	-				-0.8
1,376,261	+				-0.2
1,376,262	-				+0.2
1,376,470	+		Rv1233c	0.40	-0.2
1,376,471	-		Rv1233c	0.40	+0.8
1,376,514	-		Rv1233c	0.48	-0.5
1,376,539	+		Rv1233c	0.52	-0.3
1,376,539	+		Rv1233c	0.52	+3.6
1,376,539	+		Rv1233c	0.52	+3.3
1,376,539	+		Rv1233c	0.52	+0.3
1,376,539	+		Rv1233c	0.52	+0.3
1,376,540	-		Rv1233c	0.52	-0.4
1,376,540	-		Rv1233c	0.52	-0.1
1,376,540	-		Rv1233c	0.52	-0.5
1,376,540	-		Rv1233c	0.52	-0.7
1,376,540	-		Rv1233c	0.52	-0.8
1,376,595	-		Rv1233c	0.61	+1.3
1,376,645	+		Rv1233c	0.70	+0.3
1,376,897	-				-1.3
1,376,911	-				-0.4
1,376,982	-				-0.4
1,377,130	-		Rv1234	0.29	-0.5