Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv1194c

Experiment: 7H9 with Levofloxacin 0.3 ug/mL

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

Per-strain Table

Position	Strand	Gene	LocusTag	Fraction	7H9 with Levofloxacin 0.3 ug/mL
1,336,332	-		Rv1193	0.38	-0.5
1,336,437	-		Rv1193	0.45	-1.0
1,336,437	-		Rv1193	0.45	-0.5
1,336,617	-		Rv1193	0.58	+0.3
1,337,058	+		Rv1193	0.89	+1.3
1,337,151	+				+2.3
1,337,152	-				+0.3
1,337,265	+				+0.8
1,337,288	-				+0.2
1,337,318	-				-1.0
1,337,409	+		Rv1194c	0.13	-2.7
1,337,409	+		Rv1194c	0.13	-1.0
1,337,867	+		Rv1194c	0.49	-1.8
1,338,218	-		Rv1194c	0.77	-0.8
1,338,326	+		Rv1194c	0.85	-0.7
1,338,327	-		Rv1194c	0.85	-1.0
1,338,327	-		Rv1194c	0.85	-1.9
1,338,551	+				-1.9
1,338,551	+				-0.3
1,338,551	+				-0.0
1,338,552	-				-2.0
1,338,552	-				+0.7
1,338,552	-				-1.2
1,338,552	-				+1.4
1,338,562	+				-0.9
1,338,562	+				-0.3
1,338,562	+				+1.4
1,338,563	-				-0.4
1,338,563	-				-0.3
1,338,691	+				-1.5
1,338,691	+				-1.7
1,338,692	-				+0.7
1,338,694	+				-0.9
1,338,694	+				+0.4
1,338,703	+				-2.3
1,338,704	-				+1.0
1,338,788	+				-1.3
1,338,788	+				-1.1
1,338,789	-				-2.1
1,338,789	-				-1.4
1,338,923	-				+1.5
1,338,963	-				-0.6
1,339,021	+				+0.2
1,339,022	-				-0.5
1,339,071	+		Rv1195	0.23	-0.2
1,339,186	+		Rv1195	0.61	-0.6
1,339,187	-		Rv1195	0.61	-0.2
1,339,187	-		Rv1195	0.61	-0.7
1,339,187	-		Rv1195	0.61	+0.8
1,339,262	-		Rv1195	0.86	-1.5
1,339,262	-		Rv1195	0.86	-0.4
1,339,301	-				-0.1
1,339,301	-				+0.3
1,339,301	-				-0.0
1,339,301	-				+0.6
1,339,337	+				-0.4
1,339,338	-				+1.6
1,339,348	-				+1.2
1,339,348	-				+2.3
1,339,348	-				-1.1
1,339,348	-				+1.1
1,339,348	-				-1.6
1,339,348	-				-0.1
1,339,348	-				-0.6
1,339,348	-				+2.1
1,339,397	+				-0.4