Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv1191

Experiment: 7H9 with Levofloxacin 0.3 ug/mL

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

Per-strain Table

Position	Strand	Gene	LocusTag	Fraction	7H9 with Levofloxacin 0.3 ug/mL
1,333,297	-		Rv1190	0.36	-0.4
1,333,605	-		Rv1190	0.71	+0.9
1,333,605	-		Rv1190	0.71	-1.0
1,333,637	+		Rv1190	0.75	-1.6
1,333,637	+		Rv1190	0.75	+0.7
1,333,638	-		Rv1190	0.75	-0.6
1,333,924	-				-0.2
1,334,093	+		Rv1191	0.18	+2.3
1,334,110	+		Rv1191	0.20	-1.8
1,334,264	+		Rv1191	0.36	+0.0
1,334,264	+		Rv1191	0.36	+0.7
1,334,264	+		Rv1191	0.36	-0.1
1,334,264	+		Rv1191	0.36	-1.3
1,334,265	-		Rv1191	0.37	-1.7
1,334,265	-		Rv1191	0.37	+2.3
1,334,265	-		Rv1191	0.37	-0.3
1,334,486	+		Rv1191	0.61	-0.8
1,334,907	-				-0.7
1,334,918	+				+0.0
1,334,918	+				-0.5
1,334,919	-				+1.1
1,334,919	-				+0.7
1,334,921	+				-0.1
1,334,921	+				+0.0
1,334,922	-				-0.7
1,334,922	-				-0.8
1,334,922	-				+0.4
1,334,943	+				-0.5
1,334,987	+				-0.1
1,334,988	-				-0.7
1,334,988	-				-1.3
1,335,021	-		Rv1192	0.11	-0.2
1,335,094	-		Rv1192	0.20	-1.8
1,335,497	+		Rv1192	0.69	-0.2
1,335,709	+				-1.0