Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv1165

Experiment: 7H9 with Levofloxacin 0.3 ug/mL

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

Per-strain Table

Position	Strand	Gene	LocusTag	Fraction	7H9 with Levofloxacin 0.3 ug/mL
1,293,318	+		Rv1163	0.86	-0.6
1,293,499	+		Rv1164	0.13	-1.3
1,293,538	+		Rv1164	0.18	-0.6
1,293,742	+		Rv1164	0.45	+1.3
1,293,802	+		Rv1164	0.53	+0.2
1,293,802	+		Rv1164	0.53	-1.0
1,293,927	-		Rv1164	0.70	+0.4
1,293,964	+		Rv1164	0.75	+0.7
1,293,965	-		Rv1164	0.75	-0.3
1,293,965	-		Rv1164	0.75	+0.1
1,293,965	-		Rv1164	0.75	-0.6
1,293,967	+		Rv1164	0.76	-0.3
1,293,968	-		Rv1164	0.76	-1.5
1,294,054	+		Rv1164	0.87	+0.7
1,294,070	-		Rv1164	0.90	+0.3
1,294,144	+				+0.2
1,294,144	+				-0.5
1,294,144	+				-2.5
1,294,145	-				+0.8
1,294,145	-				-0.2
1,294,383	-		Rv1165	0.11	+2.7
1,294,394	+		Rv1165	0.12	-0.6
1,294,395	-		Rv1165	0.12	-0.1
1,294,395	-		Rv1165	0.12	-0.2
1,294,395	-		Rv1165	0.12	-0.9
1,294,518	+		Rv1165	0.19	+0.2
1,294,518	+		Rv1165	0.19	+1.8
1,294,519	-		Rv1165	0.19	-0.4
1,294,519	-		Rv1165	0.19	-0.3
1,294,622	+		Rv1165	0.24	+0.3
1,294,622	+		Rv1165	0.24	+0.1
1,294,623	-		Rv1165	0.24	+2.1
1,294,623	-		Rv1165	0.24	-0.3
1,294,623	-		Rv1165	0.24	+2.2
1,294,897	+		Rv1165	0.39	+0.2
1,294,897	+		Rv1165	0.39	-0.6
1,295,461	+		Rv1165	0.69	-1.2
1,295,462	-		Rv1165	0.69	-1.9
1,295,462	-		Rv1165	0.69	-0.0
1,295,462	-		Rv1165	0.69	-0.0
1,295,782	+		Rv1165	0.86	-0.0
1,295,939	+				+0.4
1,295,939	+				+0.3
1,295,939	+				-0.1
1,295,939	+				-0.9
1,295,940	-				-1.3
1,296,053	-				+1.0
1,296,125	-				+0.7
1,296,138	+				+0.0