Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv1139c

Experiment: 7H9 with Levofloxacin 0.3 ug/mL

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

Per-strain Table

Position	Strand	Gene	LocusTag	Fraction	7H9 with Levofloxacin 0.3 ug/mL
1,265,920	+		Rv1138c	0.44	-0.6
1,265,920	+		Rv1138c	0.44	-0.4
1,265,921	-		Rv1138c	0.44	-0.3
1,265,921	-		Rv1138c	0.44	-0.2
1,266,269	-		Rv1138c	0.78	-1.1
1,266,488	+				+1.9
1,266,624	+		Rv1139c	0.28	-0.4
1,266,625	-		Rv1139c	0.28	-0.1
1,266,788	+		Rv1139c	0.60	-1.3
1,266,867	+		Rv1139c	0.76	-1.3
1,266,867	+		Rv1139c	0.76	-0.9
1,266,868	-		Rv1139c	0.76	-2.0
1,266,978	+				-0.9
1,266,979	-				-1.7
1,266,979	-				+0.3
1,266,979	-				-0.3
1,266,982	-				-0.2
1,266,982	-				+0.3
1,266,982	-				-2.0
1,266,991	+				-1.4
1,266,991	+				-1.1
1,267,032	+				-0.2
1,267,085	+				-0.2
1,267,086	-				+0.1
1,267,086	-				+0.8
1,267,110	-				-0.3
1,267,319	-				-1.3
1,267,804	+		Rv1140	0.54	-0.7
1,267,805	-		Rv1140	0.54	+0.6