Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv0963c

Experiment: 7H9 with Levofloxacin 0.3 ug/mL

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv0961 and Rv0962c are separated by 18 nucleotidesRv0962c and Rv0963c are separated by 182 nucleotidesRv0963c and Rv0964c are separated by 98 nucleotidesRv0964c and Rv0965c are separated by 99 nucleotides Rv0961: Rv0961 - Probable integral membrane protein, at 1,074,074 to 1,074,421 Rv0961 Rv0962c: Rv0962c - Possible lipoprotein LprP, at 1,074,440 to 1,075,114 Rv0962c Rv0963c: Rv0963c - Conserved hypothetical protein, at 1,075,297 to 1,076,097 Rv0963c Rv0964c: Rv0964c - Hypothetical protein, at 1,076,196 to 1,076,678 Rv0964c Rv0965c: Rv0965c - Conserved hypothetical protein, at 1,076,778 to 1,077,197 Rv0965c Position (kb) 1075 1076 1077Strain fitness (log2 ratio) -2 -1 0 1 2at 1074.392 kb on + strandat 1074.393 kb on - strandat 1074.393 kb on - strandat 1074.445 kb on - strandat 1074.478 kb on - strandat 1074.478 kb on - strandat 1074.576 kb on + strand, within Rv0962cat 1074.576 kb on + strand, within Rv0962cat 1074.577 kb on - strand, within Rv0962cat 1074.577 kb on - strand, within Rv0962cat 1074.577 kb on - strand, within Rv0962cat 1074.582 kb on + strand, within Rv0962cat 1074.620 kb on + strand, within Rv0962cat 1074.791 kb on + strand, within Rv0962cat 1074.791 kb on + strand, within Rv0962cat 1074.791 kb on + strand, within Rv0962cat 1075.036 kb on + strand, within Rv0962cat 1075.036 kb on + strand, within Rv0962cat 1075.037 kb on - strand, within Rv0962cat 1075.049 kb on - strandat 1075.122 kb on - strandat 1075.136 kb on - strandat 1075.241 kb on + strandat 1075.275 kb on + strandat 1075.298 kb on + strandat 1075.298 kb on + strandat 1075.425 kb on + strand, within Rv0963cat 1075.425 kb on + strand, within Rv0963cat 1075.425 kb on + strand, within Rv0963cat 1075.457 kb on + strand, within Rv0963cat 1075.458 kb on - strand, within Rv0963cat 1075.523 kb on + strand, within Rv0963cat 1075.524 kb on - strand, within Rv0963cat 1075.728 kb on - strand, within Rv0963cat 1075.760 kb on + strand, within Rv0963cat 1075.761 kb on - strand, within Rv0963cat 1075.993 kb on - strand, within Rv0963cat 1076.474 kb on - strand, within Rv0964cat 1076.520 kb on + strand, within Rv0964cat 1076.521 kb on - strand, within Rv0964cat 1076.631 kb on + strandat 1076.632 kb on - strandat 1076.784 kb on - strandat 1076.784 kb on - strandat 1076.899 kb on + strand, within Rv0965cat 1076.899 kb on + strand, within Rv0965c

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Levofloxacin 0.3 ug/mL
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1,074,392 + -0.8
1,074,393 - -0.8
1,074,393 - +0.8
1,074,445 - +0.1
1,074,478 - -2.6
1,074,478 - -0.9
1,074,576 + Rv0962c 0.20 -0.3
1,074,576 + Rv0962c 0.20 +0.2
1,074,577 - Rv0962c 0.20 -0.9
1,074,577 - Rv0962c 0.20 -0.1
1,074,577 - Rv0962c 0.20 +0.3
1,074,582 + Rv0962c 0.21 -0.9
1,074,620 + Rv0962c 0.27 -0.3
1,074,791 + Rv0962c 0.52 -1.5
1,074,791 + Rv0962c 0.52 -1.1
1,074,791 + Rv0962c 0.52 -0.6
1,075,036 + Rv0962c 0.88 -2.2
1,075,036 + Rv0962c 0.88 -1.7
1,075,037 - Rv0962c 0.88 +1.2
1,075,049 - -0.3
1,075,122 - -0.8
1,075,136 - +0.6
1,075,241 + -0.7
1,075,275 + -0.9
1,075,298 + -0.1
1,075,298 + -0.1
1,075,425 + Rv0963c 0.16 +0.6
1,075,425 + Rv0963c 0.16 -0.8
1,075,425 + Rv0963c 0.16 +2.2
1,075,457 + Rv0963c 0.20 -0.8
1,075,458 - Rv0963c 0.20 +0.4
1,075,523 + Rv0963c 0.28 -1.0
1,075,524 - Rv0963c 0.28 -1.3
1,075,728 - Rv0963c 0.54 -0.1
1,075,760 + Rv0963c 0.58 +1.2
1,075,761 - Rv0963c 0.58 +0.2
1,075,993 - Rv0963c 0.87 +0.5
1,076,474 - Rv0964c 0.58 -0.1
1,076,520 + Rv0964c 0.67 -1.1
1,076,521 - Rv0964c 0.67 +1.2
1,076,631 + -0.3
1,076,632 - +1.6
1,076,784 - +0.6
1,076,784 - -0.6
1,076,899 + Rv0965c 0.29 +0.7
1,076,899 + Rv0965c 0.29 -1.3

Or see this region's nucleotide sequence