Experiment: 7H9 with Levofloxacin 0.3 ug/mL
Only strains with sufficient reads to estimate fitness are shown,
but the strain fitness values are still rather noisy and may be biased towards zero.
Strains near the edge of a gene are not shown as being associated with that
gene (they are in grey).
Strains in the central 10-90% of a gene are color coded by the insertion's strand.
Usually, "+" means that the selectable marker is encoded on the forward strand,
i.e., transcribed rightward.
500 nt Rv0935 and Rv0936 are separated by 1 nucleotides Rv0936 and Rv0937c overlap by 24 nucleotides Rv0937c and Rv0938 are separated by 115 nucleotides
Rv0935: Rv0935 - Phosphate-transport integral membrane ABC transporter PstC1, at 1,043,299 to 1,044,315
Rv0935
Rv0936: Rv0936 - Phosphate-transport integral membrane ABC transporter PstA2, at 1,044,317 to 1,045,222
Rv0936
Rv0937c: Rv0937c - DNA end-binding protein, Mku, at 1,045,199 to 1,046,020
Rv0937c
Rv0938: Rv0938 - ATP dependent DNA ligase LigD (ATP dependent polydeoxyribonucleotide synthase) (thermostable DNA ligase) (ATP dependent polynucleotide ligase) (sealase) (DNA repair enzyme) (DNA joinase), at 1,046,136 to 1,048,415
Rv0938
Position (kb)
1044
1045
1046 Strain fitness (log2 ratio)
-2
-1
0
1
2 at 1043.360 kb on + strand at 1043.360 kb on + strand at 1043.360 kb on + strand at 1043.361 kb on - strand at 1043.361 kb on - strand at 1043.488 kb on + strand, within Rv0935 at 1043.615 kb on + strand, within Rv0935 at 1043.675 kb on + strand, within Rv0935 at 1043.675 kb on + strand, within Rv0935 at 1043.676 kb on - strand, within Rv0935 at 1043.809 kb on + strand, within Rv0935 at 1043.810 kb on - strand, within Rv0935 at 1043.810 kb on - strand, within Rv0935 at 1043.887 kb on - strand, within Rv0935 at 1044.115 kb on + strand, within Rv0935 at 1044.116 kb on - strand, within Rv0935 at 1044.116 kb on - strand, within Rv0935 at 1044.246 kb on + strand at 1044.247 kb on - strand at 1044.351 kb on + strand at 1044.386 kb on + strand at 1044.386 kb on + strand at 1044.752 kb on + strand, within Rv0936 at 1044.753 kb on - strand, within Rv0936 at 1044.815 kb on + strand, within Rv0936 at 1044.816 kb on - strand, within Rv0936 at 1045.656 kb on + strand, within Rv0937c at 1045.830 kb on + strand, within Rv0937c at 1046.022 kb on + strand at 1046.022 kb on + strand at 1046.023 kb on - strand at 1046.023 kb on - strand at 1046.030 kb on + strand at 1046.030 kb on + strand at 1046.030 kb on + strand at 1046.124 kb on + strand at 1046.124 kb on + strand at 1046.125 kb on - strand at 1046.191 kb on - strand
Per-strain Table
Position Strand Gene LocusTag Fraction 7H9 with Levofloxacin 0.3 ug/mL remove 1,043,360 + -0.6 1,043,360 + +2.5 1,043,360 + +0.2 1,043,361 - +0.9 1,043,361 - +2.2 1,043,488 + Rv0935 0.19 -0.5 1,043,615 + Rv0935 0.31 -0.4 1,043,675 + Rv0935 0.37 -0.4 1,043,675 + Rv0935 0.37 +0.2 1,043,676 - Rv0935 0.37 -1.1 1,043,809 + Rv0935 0.50 -1.2 1,043,810 - Rv0935 0.50 +0.2 1,043,810 - Rv0935 0.50 +0.4 1,043,887 - Rv0935 0.58 -0.5 1,044,115 + Rv0935 0.80 -1.6 1,044,116 - Rv0935 0.80 -0.1 1,044,116 - Rv0935 0.80 -0.6 1,044,246 + -0.1 1,044,247 - +0.8 1,044,351 + +1.2 1,044,386 + -1.2 1,044,386 + -0.9 1,044,752 + Rv0936 0.48 +0.2 1,044,753 - Rv0936 0.48 -1.0 1,044,815 + Rv0936 0.55 -0.5 1,044,816 - Rv0936 0.55 -1.4 1,045,656 + Rv0937c 0.56 -1.5 1,045,830 + Rv0937c 0.77 -1.9 1,046,022 + +0.2 1,046,022 + -0.6 1,046,023 - -1.2 1,046,023 - +1.2 1,046,030 + -0.9 1,046,030 + -0.6 1,046,030 + +0.6 1,046,124 + -0.4 1,046,124 + -1.2 1,046,125 - -0.6 1,046,191 - -0.6
Or see this region's nucleotide sequence