Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv0892

Experiment: 7H9 with Levofloxacin 0.3 ug/mL

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv0891c and Rv0892 are separated by 397 nucleotidesRv0892 and Rv0893c overlap by 23 nucleotides Rv0891c: Rv0891c - Possible transcriptional regulatory protein, at 992,598 to 993,455 Rv0891c Rv0892: Rv0892 - Probable monooxygenase, at 993,853 to 995,340 Rv0892 Rv0893c: Rv0893c - Possible S-adenosylmethionine-dependent methyltransferase, at 995,318 to 996,295 Rv0893c Position (kb) 993 994 995 996Strain fitness (log2 ratio) -2 -1 0 1 2 3at 992.916 kb on + strand, within Rv0891cat 992.917 kb on - strand, within Rv0891cat 992.937 kb on + strand, within Rv0891cat 992.938 kb on - strand, within Rv0891cat 992.938 kb on - strand, within Rv0891cat 992.939 kb on + strand, within Rv0891cat 992.940 kb on - strand, within Rv0891cat 992.940 kb on - strand, within Rv0891cat 992.943 kb on + strand, within Rv0891cat 992.943 kb on + strand, within Rv0891cat 992.943 kb on + strand, within Rv0891cat 993.029 kb on + strand, within Rv0891cat 993.029 kb on + strand, within Rv0891cat 993.030 kb on - strand, within Rv0891cat 993.216 kb on + strand, within Rv0891cat 993.341 kb on + strand, within Rv0891cat 993.342 kb on - strand, within Rv0891cat 993.434 kb on + strandat 993.477 kb on - strandat 993.526 kb on + strandat 993.527 kb on - strandat 993.748 kb on + strandat 993.751 kb on - strandat 994.263 kb on - strand, within Rv0892at 994.479 kb on + strand, within Rv0892at 994.547 kb on - strand, within Rv0892at 994.548 kb on + strand, within Rv0892at 994.555 kb on + strand, within Rv0892at 994.558 kb on - strand, within Rv0892at 995.198 kb on - strandat 995.271 kb on - strandat 995.319 kb on + strandat 995.345 kb on + strandat 995.388 kb on - strandat 995.420 kb on - strand, within Rv0893cat 995.867 kb on + strand, within Rv0893cat 996.105 kb on + strand, within Rv0893c

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Levofloxacin 0.3 ug/mL
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992,916 + Rv0891c 0.37 -0.4
992,917 - Rv0891c 0.37 +0.1
992,937 + Rv0891c 0.40 -1.8
992,938 - Rv0891c 0.40 -1.6
992,938 - Rv0891c 0.40 -1.0
992,939 + Rv0891c 0.40 -0.2
992,940 - Rv0891c 0.40 -1.4
992,940 - Rv0891c 0.40 -0.9
992,943 + Rv0891c 0.40 +3.2
992,943 + Rv0891c 0.40 -0.5
992,943 + Rv0891c 0.40 -0.5
993,029 + Rv0891c 0.50 +0.6
993,029 + Rv0891c 0.50 +1.6
993,030 - Rv0891c 0.50 +0.9
993,216 + Rv0891c 0.72 -0.8
993,341 + Rv0891c 0.87 +0.6
993,342 - Rv0891c 0.87 +0.1
993,434 + -0.2
993,477 - +0.6
993,526 + +0.1
993,527 - +2.2
993,748 + -0.6
993,751 - +0.6
994,263 - Rv0892 0.28 -0.4
994,479 + Rv0892 0.42 +2.2
994,547 - Rv0892 0.47 -0.8
994,548 + Rv0892 0.47 -0.0
994,555 + Rv0892 0.47 +0.6
994,558 - Rv0892 0.47 -1.0
995,198 - +0.1
995,271 - -0.4
995,319 + +0.0
995,345 + +3.5
995,388 - -1.3
995,420 - Rv0893c 0.10 -0.4
995,867 + Rv0893c 0.56 +2.2
996,105 + Rv0893c 0.80 -0.9

Or see this region's nucleotide sequence