Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv0690c

Experiment: 7H9 with Levofloxacin 0.3 ug/mL

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv0688 and Rv0689c overlap by 4 nucleotidesRv0689c and Rv0690c are separated by 612 nucleotidesRv0690c and Rv0691c overlap by 4 nucleotidesRv0691c and Rv0691A overlap by 9 nucleotidesRv0691A and Rv0692 overlap by 16 nucleotides Rv0688: Rv0688 - Putative ferredoxin reductase, at 787,940 to 789,160 Rv0688 Rv0689c: Rv0689c - Hypothetical protein, at 789,157 to 789,411 Rv0689c Rv0690c: Rv0690c - Conserved hypothetical protein, at 790,024 to 791,073 Rv0690c Rv0691c: Rv0691c - Probable transcriptional regulatory protein, at 791,070 to 791,666 Rv0691c Rv0691A: Rv0691A - Mycofactocin precursor protein, at 791,658 to 791,846 Rv0691A Rv0692: Rv0692 - Conserved hypothetical protein, at 791,831 to 792,160 Rv0692 Position (kb) 790 791 792Strain fitness (log2 ratio) -2 -1 0 1 2at 789.032 kb on + strand, within Rv0688at 789.036 kb on - strand, within Rv0688at 789.142 kb on - strandat 789.170 kb on - strandat 789.213 kb on + strand, within Rv0689cat 789.213 kb on + strand, within Rv0689cat 789.214 kb on - strand, within Rv0689cat 789.214 kb on - strand, within Rv0689cat 789.418 kb on + strandat 789.419 kb on - strandat 789.695 kb on + strandat 789.696 kb on - strandat 790.101 kb on + strandat 790.102 kb on - strandat 790.105 kb on + strandat 790.106 kb on - strandat 790.106 kb on - strandat 790.106 kb on - strandat 790.106 kb on - strandat 790.113 kb on - strandat 790.244 kb on + strand, within Rv0690cat 790.413 kb on - strand, within Rv0690cat 790.577 kb on + strand, within Rv0690cat 790.628 kb on - strand, within Rv0690cat 790.998 kb on - strandat 790.998 kb on - strandat 791.167 kb on + strand, within Rv0691cat 791.284 kb on + strand, within Rv0691cat 791.284 kb on + strand, within Rv0691cat 791.284 kb on + strand, within Rv0691cat 791.285 kb on - strand, within Rv0691cat 791.285 kb on - strand, within Rv0691cat 791.299 kb on + strand, within Rv0691cat 791.841 kb on + strandat 791.917 kb on - strand, within Rv0692at 791.980 kb on + strand, within Rv0692at 791.980 kb on + strand, within Rv0692at 791.981 kb on - strand, within Rv0692

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Levofloxacin 0.3 ug/mL
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789,032 + Rv0688 0.89 +1.2
789,036 - Rv0688 0.90 -0.8
789,142 - +1.0
789,170 - -0.7
789,213 + Rv0689c 0.22 +0.4
789,213 + Rv0689c 0.22 -0.8
789,214 - Rv0689c 0.22 -0.8
789,214 - Rv0689c 0.22 -0.2
789,418 + -0.2
789,419 - +0.7
789,695 + -1.0
789,696 - -1.1
790,101 + -0.3
790,102 - -0.8
790,105 + -0.4
790,106 - -0.6
790,106 - +0.2
790,106 - -0.5
790,106 - +0.3
790,113 - -0.4
790,244 + Rv0690c 0.21 -0.3
790,413 - Rv0690c 0.37 -0.5
790,577 + Rv0690c 0.53 -0.8
790,628 - Rv0690c 0.58 -1.5
790,998 - -1.0
790,998 - -1.5
791,167 + Rv0691c 0.16 +1.2
791,284 + Rv0691c 0.36 +0.7
791,284 + Rv0691c 0.36 -1.9
791,284 + Rv0691c 0.36 +0.0
791,285 - Rv0691c 0.36 +0.2
791,285 - Rv0691c 0.36 -1.1
791,299 + Rv0691c 0.38 -1.6
791,841 + -0.7
791,917 - Rv0692 0.26 -1.0
791,980 + Rv0692 0.45 -2.6
791,980 + Rv0692 0.45 +2.0
791,981 - Rv0692 0.45 +0.5

Or see this region's nucleotide sequence