Experiment: 7H9 with Levofloxacin 0.3 ug/mL
Only strains with sufficient reads to estimate fitness are shown,
but the strain fitness values are still rather noisy and may be biased towards zero.
Strains near the edge of a gene are not shown as being associated with that
gene (they are in grey).
Strains in the central 10-90% of a gene are color coded by the insertion's strand.
Usually, "+" means that the selectable marker is encoded on the forward strand,
i.e., transcribed rightward.
500 nt Rv0473 and Rv0474 are separated by 86 nucleotides Rv0474 and Rv0475 are separated by 353 nucleotides Rv0475 and Rv0476 are separated by 111 nucleotides Rv0476 and Rv0477 are separated by 4 nucleotides Rv0477 and Rv0478 overlap by 1 nucleotides
Rv0473: Rv0473 - Possible conserved transmembrane protein, at 563,564 to 564,934
Rv0473
Rv0474: Rv0474 - Probable transcriptional regulatory protein, at 565,021 to 565,443
Rv0474
Rv0475: Rv0475 - Iron-regulated heparin binding hemagglutinin HbhA (adhesin), at 565,797 to 566,396
Rv0475
Rv0476: Rv0476 - Possible conserved transmembrane protein, at 566,508 to 566,771
Rv0476
Rv0477: Rv0477 - Possible conserved secreted protein, at 566,776 to 567,222
Rv0477
Rv0478: Rv0478 - Probable deoxyribose-phosphate aldolase DeoC (phosphodeoxyriboaldolase) (deoxyriboaldolase), at 567,222 to 567,896
Rv0478
Position (kb) 565
566
567 Strain fitness (log2 ratio) -3
-2
-1
0
1
2
3
4 at 564.908 kb on + strand at 564.908 kb on + strand at 564.975 kb on + strand at 564.976 kb on - strand at 564.976 kb on - strand at 565.009 kb on + strand at 565.009 kb on + strand at 565.015 kb on + strand at 565.016 kb on - strand at 565.198 kb on - strand, within Rv0474 at 565.261 kb on + strand, within Rv0474 at 565.262 kb on - strand, within Rv0474 at 565.262 kb on - strand, within Rv0474 at 565.326 kb on + strand, within Rv0474 at 565.365 kb on + strand, within Rv0474 at 565.369 kb on + strand, within Rv0474 at 565.369 kb on + strand, within Rv0474 at 565.369 kb on + strand, within Rv0474 at 565.380 kb on + strand, within Rv0474 at 565.380 kb on + strand, within Rv0474 at 565.380 kb on + strand, within Rv0474 at 565.380 kb on + strand, within Rv0474 at 565.380 kb on + strand, within Rv0474 at 565.381 kb on - strand, within Rv0474 at 565.592 kb on + strand at 565.592 kb on + strand at 565.592 kb on + strand at 565.592 kb on + strand at 565.592 kb on + strand at 565.592 kb on + strand at 565.592 kb on + strand at 565.593 kb on - strand at 565.593 kb on - strand at 565.593 kb on - strand at 565.593 kb on - strand at 565.593 kb on - strand at 565.593 kb on - strand at 565.621 kb on + strand at 565.621 kb on + strand at 565.622 kb on - strand at 565.704 kb on - strand at 565.704 kb on - strand at 565.704 kb on - strand at 565.704 kb on - strand at 565.754 kb on + strand at 565.754 kb on + strand at 565.755 kb on - strand at 565.755 kb on - strand at 565.755 kb on - strand at 565.755 kb on - strand at 565.776 kb on + strand at 565.780 kb on + strand at 565.780 kb on + strand at 565.780 kb on + strand at 565.781 kb on - strand at 565.781 kb on - strand at 566.039 kb on + strand, within Rv0475 at 566.080 kb on - strand, within Rv0475 at 566.114 kb on - strand, within Rv0475 at 566.169 kb on + strand, within Rv0475 at 566.170 kb on - strand, within Rv0475 at 566.276 kb on + strand, within Rv0475 at 566.276 kb on + strand, within Rv0475 at 566.277 kb on - strand, within Rv0475 at 566.394 kb on + strand at 566.394 kb on + strand at 566.395 kb on - strand at 566.395 kb on - strand at 566.516 kb on - strand at 566.516 kb on - strand at 566.547 kb on + strand, within Rv0476 at 566.547 kb on + strand, within Rv0476 at 566.586 kb on + strand, within Rv0476 at 566.586 kb on + strand, within Rv0476 at 566.586 kb on + strand, within Rv0476 at 566.587 kb on - strand, within Rv0476 at 566.589 kb on - strand, within Rv0476 at 566.719 kb on - strand, within Rv0476 at 566.828 kb on + strand, within Rv0477 at 566.828 kb on + strand, within Rv0477 at 566.829 kb on - strand, within Rv0477 at 566.829 kb on - strand, within Rv0477 at 566.881 kb on + strand, within Rv0477 at 566.881 kb on + strand, within Rv0477 at 566.881 kb on + strand, within Rv0477 at 566.881 kb on + strand, within Rv0477 at 566.881 kb on + strand, within Rv0477 at 566.882 kb on - strand, within Rv0477 at 566.882 kb on - strand, within Rv0477 at 566.882 kb on - strand, within Rv0477 at 566.882 kb on - strand, within Rv0477 at 566.882 kb on - strand, within Rv0477 at 566.982 kb on + strand, within Rv0477 at 566.983 kb on - strand, within Rv0477 at 567.101 kb on - strand, within Rv0477 at 567.101 kb on - strand, within Rv0477 at 567.262 kb on + strand at 567.342 kb on + strand, within Rv0478
Per-strain Table
Position Strand Gene LocusTag Fraction 7H9 with Levofloxacin 0.3 ug/mL remove 564,908 + +1.8 564,908 + -0.2 564,975 + -1.3 564,976 - -0.9 564,976 - +2.1 565,009 + -0.9 565,009 + -0.8 565,015 + -0.7 565,016 - -0.3 565,198 - Rv0474 0.42 -0.3 565,261 + Rv0474 0.57 +4.3 565,262 - Rv0474 0.57 -0.3 565,262 - Rv0474 0.57 -2.9 565,326 + Rv0474 0.72 -1.6 565,365 + Rv0474 0.81 -0.8 565,369 + Rv0474 0.82 -1.0 565,369 + Rv0474 0.82 -0.6 565,369 + Rv0474 0.82 -0.8 565,380 + Rv0474 0.85 -2.7 565,380 + Rv0474 0.85 +2.3 565,380 + Rv0474 0.85 -1.0 565,380 + Rv0474 0.85 -2.1 565,380 + Rv0474 0.85 -3.3 565,381 - Rv0474 0.85 -0.2 565,592 + -0.4 565,592 + -1.6 565,592 + -1.1 565,592 + -2.4 565,592 + -0.3 565,592 + +0.4 565,592 + +0.2 565,593 - -1.4 565,593 - -1.2 565,593 - +0.0 565,593 - +0.1 565,593 - -1.0 565,593 - -0.4 565,621 + +0.1 565,621 + +0.8 565,622 - +0.7 565,704 - -1.2 565,704 - -0.3 565,704 - +2.0 565,704 - -0.4 565,754 + -0.4 565,754 + +2.0 565,755 - -0.0 565,755 - +0.1 565,755 - -2.4 565,755 - +1.8 565,776 + +3.6 565,780 + -0.8 565,780 + -1.6 565,780 + +0.9 565,781 - -1.4 565,781 - -1.8 566,039 + Rv0475 0.40 +2.3 566,080 - Rv0475 0.47 -0.1 566,114 - Rv0475 0.53 +2.0 566,169 + Rv0475 0.62 +0.7 566,170 - Rv0475 0.62 -0.1 566,276 + Rv0475 0.80 +1.1 566,276 + Rv0475 0.80 -0.4 566,277 - Rv0475 0.80 -0.5 566,394 + -0.8 566,394 + -1.0 566,395 - -0.9 566,395 - +0.0 566,516 - -1.2 566,516 - -0.6 566,547 + Rv0476 0.15 -0.1 566,547 + Rv0476 0.15 +0.3 566,586 + Rv0476 0.30 +0.1 566,586 + Rv0476 0.30 -1.1 566,586 + Rv0476 0.30 +0.7 566,587 - Rv0476 0.30 -1.7 566,589 - Rv0476 0.31 +1.0 566,719 - Rv0476 0.80 +3.6 566,828 + Rv0477 0.12 -0.2 566,828 + Rv0477 0.12 +1.0 566,829 - Rv0477 0.12 +1.0 566,829 - Rv0477 0.12 -2.6 566,881 + Rv0477 0.23 -2.1 566,881 + Rv0477 0.23 -1.3 566,881 + Rv0477 0.23 -1.1 566,881 + Rv0477 0.23 -0.1 566,881 + Rv0477 0.23 -0.7 566,882 - Rv0477 0.24 +1.0 566,882 - Rv0477 0.24 -0.2 566,882 - Rv0477 0.24 -1.4 566,882 - Rv0477 0.24 +1.0 566,882 - Rv0477 0.24 -0.4 566,982 + Rv0477 0.46 -1.3 566,983 - Rv0477 0.46 -0.1 567,101 - Rv0477 0.73 +0.4 567,101 - Rv0477 0.73 +0.0 567,262 + -1.0 567,342 + Rv0478 0.18 -0.3
Or see this region's nucleotide sequence