Experiment: 7H9 with Levofloxacin 0.3 ug/mL
Only strains with sufficient reads to estimate fitness are shown,
but the strain fitness values are still rather noisy and may be biased towards zero.
Strains near the edge of a gene are not shown as being associated with that
gene (they are in grey).
Strains in the central 10-90% of a gene are color coded by the insertion's strand.
Usually, "+" means that the selectable marker is encoded on the forward strand,
i.e., transcribed rightward.
500 nt Rv0450c and Rv0451c overlap by 4 nucleotides Rv0451c and Rv0452 are separated by 231 nucleotides Rv0452 and Rv0453 are separated by 321 nucleotides
Rv0450c: Rv0450c - Probable conserved transmembrane transport protein MmpL4, at 538,588 to 541,491
Rv0450c
Rv0451c: Rv0451c - Probable conserved membrane protein MmpS4, at 541,488 to 541,910
Rv0451c
Rv0452: Rv0452 - Possible transcriptional regulatory protein, at 542,142 to 542,852
Rv0452
Rv0453: Rv0453 - PPE family protein PPE11, at 543,174 to 544,730
Rv0453
Position (kb) 542
543 Strain fitness (log2 ratio) -3
-2
-1
0
1
2 at 541.510 kb on + strand at 541.644 kb on - strand, within Rv0451c at 541.801 kb on + strand, within Rv0451c at 541.905 kb on + strand at 541.906 kb on - strand at 541.906 kb on - strand at 541.906 kb on - strand at 541.995 kb on + strand at 541.995 kb on + strand at 542.009 kb on + strand at 542.038 kb on - strand at 542.038 kb on - strand at 542.059 kb on + strand at 542.059 kb on + strand at 542.060 kb on - strand at 542.079 kb on - strand at 542.107 kb on + strand at 542.107 kb on + strand at 542.107 kb on + strand at 542.107 kb on + strand at 542.107 kb on + strand at 542.107 kb on + strand at 542.107 kb on + strand at 542.108 kb on - strand at 542.399 kb on - strand, within Rv0452 at 542.582 kb on - strand, within Rv0452 at 542.658 kb on + strand, within Rv0452 at 542.719 kb on - strand, within Rv0452 at 543.071 kb on + strand at 543.072 kb on - strand at 543.072 kb on - strand at 543.072 kb on - strand at 543.084 kb on + strand at 543.108 kb on + strand at 543.173 kb on + strand at 543.173 kb on + strand at 543.174 kb on - strand at 543.174 kb on - strand at 543.191 kb on - strand at 543.191 kb on - strand at 543.233 kb on + strand at 543.297 kb on + strand at 543.399 kb on + strand, within Rv0453 at 543.577 kb on + strand, within Rv0453 at 543.577 kb on + strand, within Rv0453 at 543.578 kb on - strand, within Rv0453 at 543.604 kb on - strand, within Rv0453 at 543.646 kb on - strand, within Rv0453 at 543.746 kb on + strand, within Rv0453 at 543.747 kb on - strand, within Rv0453
Per-strain Table
Position Strand Gene LocusTag Fraction 7H9 with Levofloxacin 0.3 ug/mL remove 541,510 + -2.9 541,644 - Rv0451c 0.37 +0.7 541,801 + Rv0451c 0.74 +0.5 541,905 + +0.0 541,906 - +0.3 541,906 - -0.6 541,906 - -1.2 541,995 + -1.3 541,995 + -0.2 542,009 + +1.4 542,038 - -0.2 542,038 - +2.0 542,059 + +0.3 542,059 + -0.6 542,060 - +0.2 542,079 - -0.9 542,107 + -0.2 542,107 + +0.6 542,107 + -0.2 542,107 + +0.0 542,107 + -0.6 542,107 + +0.1 542,107 + -0.3 542,108 - -0.4 542,399 - Rv0452 0.36 -1.4 542,582 - Rv0452 0.62 -1.1 542,658 + Rv0452 0.73 -0.9 542,719 - Rv0452 0.81 -1.2 543,071 + +0.7 543,072 - +1.6 543,072 - +0.4 543,072 - -0.6 543,084 + -0.2 543,108 + -0.8 543,173 + -0.7 543,173 + +0.4 543,174 - -0.9 543,174 - -0.5 543,191 - +0.7 543,191 - +0.3 543,233 + +0.0 543,297 + -0.7 543,399 + Rv0453 0.14 +0.4 543,577 + Rv0453 0.26 -2.5 543,577 + Rv0453 0.26 +0.8 543,578 - Rv0453 0.26 -0.2 543,604 - Rv0453 0.28 +0.3 543,646 - Rv0453 0.30 -0.4 543,746 + Rv0453 0.37 -0.5 543,747 - Rv0453 0.37 +0.4
Or see this region's nucleotide sequence