Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv0403c

Experiment: 7H9 with Levofloxacin 0.3 ug/mL

Add experiment(s):

Zoom: Pan:

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

download SVG
500 ntRv0402c and Rv0403c overlap by 4 nucleotidesRv0403c and Rv0404 are separated by 320 nucleotides Rv0402c: Rv0402c - Probable conserved transmembrane transport protein MmpL1, at 480,355 to 483,231 Rv0402c Rv0403c: Rv0403c - Probable conserved membrane protein MmpS1, at 483,228 to 483,656 Rv0403c Rv0404: Rv0404 - Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase), at 483,977 to 485,734 Rv0404 Position (kb) 483 484Strain fitness (log2 ratio) -2 -1 0 1 2 3at 482.301 kb on - strand, within Rv0402cat 482.366 kb on + strand, within Rv0402cat 482.436 kb on - strand, within Rv0402cat 482.487 kb on + strand, within Rv0402cat 482.488 kb on - strand, within Rv0402cat 482.597 kb on + strand, within Rv0402cat 482.671 kb on + strand, within Rv0402cat 482.672 kb on - strand, within Rv0402cat 482.711 kb on + strand, within Rv0402cat 482.711 kb on + strand, within Rv0402cat 482.822 kb on + strand, within Rv0402cat 482.823 kb on - strand, within Rv0402cat 482.823 kb on - strand, within Rv0402cat 482.939 kb on + strand, within Rv0402cat 483.073 kb on + strandat 483.135 kb on + strandat 483.387 kb on - strand, within Rv0403cat 483.387 kb on - strand, within Rv0403cat 483.446 kb on - strand, within Rv0403cat 483.488 kb on - strand, within Rv0403cat 483.615 kb on + strandat 483.615 kb on + strandat 483.616 kb on - strandat 483.616 kb on - strandat 483.616 kb on - strandat 483.815 kb on + strandat 483.987 kb on + strandat 484.199 kb on + strand, within Rv0404at 484.199 kb on + strand, within Rv0404at 484.300 kb on - strand, within Rv0404at 484.386 kb on + strand, within Rv0404at 484.387 kb on - strand, within Rv0404at 484.391 kb on - strand, within Rv0404at 484.411 kb on + strand, within Rv0404at 484.634 kb on + strand, within Rv0404

download strain data

Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Levofloxacin 0.3 ug/mL
remove
482,301 - Rv0402c 0.68 +0.7
482,366 + Rv0402c 0.70 -0.1
482,436 - Rv0402c 0.72 -1.2
482,487 + Rv0402c 0.74 -0.7
482,488 - Rv0402c 0.74 +2.6
482,597 + Rv0402c 0.78 +2.0
482,671 + Rv0402c 0.81 -0.5
482,672 - Rv0402c 0.81 -0.1
482,711 + Rv0402c 0.82 +0.1
482,711 + Rv0402c 0.82 -0.2
482,822 + Rv0402c 0.86 +0.3
482,823 - Rv0402c 0.86 -0.5
482,823 - Rv0402c 0.86 -1.3
482,939 + Rv0402c 0.90 -1.2
483,073 + +1.4
483,135 + +0.7
483,387 - Rv0403c 0.37 -0.2
483,387 - Rv0403c 0.37 -1.7
483,446 - Rv0403c 0.51 -1.1
483,488 - Rv0403c 0.61 -1.9
483,615 + +0.4
483,615 + +0.2
483,616 - +3.0
483,616 - -0.4
483,616 - -0.5
483,815 + -1.4
483,987 + -0.6
484,199 + Rv0404 0.13 -0.2
484,199 + Rv0404 0.13 -0.0
484,300 - Rv0404 0.18 +0.0
484,386 + Rv0404 0.23 -1.0
484,387 - Rv0404 0.23 -0.3
484,391 - Rv0404 0.24 +2.0
484,411 + Rv0404 0.25 -0.4
484,634 + Rv0404 0.37 -0.6

Or see this region's nucleotide sequence