Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv0392c

Experiment: 7H9 with Levofloxacin 0.3 ug/mL

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv0391 and Rv0392c overlap by 4 nucleotidesRv0392c and Rv0393 are separated by 141 nucleotides Rv0391: Rv0391 - Probable O-succinylhomoserine sulfhydrylase MetZ (OSH sulfhydrylase), at 470,010 to 471,230 Rv0391 Rv0392c: Rv0392c - Probable membrane NADH dehydrogenase NdhA, at 471,227 to 472,639 Rv0392c Rv0393: Rv0393 - Conserved 13E12 repeat family protein, at 472,781 to 474,106 Rv0393 Position (kb) 471 472 473Strain fitness (log2 ratio) -2 -1 0 1at 470.721 kb on + strand, within Rv0391at 470.929 kb on - strand, within Rv0391at 471.228 kb on + strandat 471.325 kb on - strandat 472.037 kb on - strand, within Rv0392cat 472.474 kb on - strand, within Rv0392cat 472.541 kb on - strandat 472.673 kb on + strandat 472.674 kb on - strandat 472.674 kb on - strandat 472.681 kb on - strandat 472.706 kb on - strandat 472.854 kb on + strandat 472.854 kb on + strandat 472.855 kb on - strandat 472.855 kb on - strandat 472.894 kb on - strandat 472.992 kb on + strand, within Rv0393at 473.103 kb on + strand, within Rv0393at 473.104 kb on - strand, within Rv0393at 473.213 kb on + strand, within Rv0393at 473.214 kb on - strand, within Rv0393at 473.214 kb on - strand, within Rv0393at 473.225 kb on + strand, within Rv0393at 473.225 kb on + strand, within Rv0393at 473.225 kb on + strand, within Rv0393at 473.226 kb on - strand, within Rv0393

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Levofloxacin 0.3 ug/mL
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470,721 + Rv0391 0.58 +0.5
470,929 - Rv0391 0.75 +0.4
471,228 + -0.1
471,325 - -0.6
472,037 - Rv0392c 0.57 -2.2
472,474 - Rv0392c 0.88 -0.7
472,541 - -1.4
472,673 + -0.4
472,674 - +0.0
472,674 - +0.3
472,681 - -0.7
472,706 - -2.0
472,854 + -1.6
472,854 + -0.3
472,855 - -0.6
472,855 - +0.1
472,894 - -0.0
472,992 + Rv0393 0.16 -0.8
473,103 + Rv0393 0.24 -0.7
473,104 - Rv0393 0.24 -1.1
473,213 + Rv0393 0.33 -0.1
473,214 - Rv0393 0.33 -0.6
473,214 - Rv0393 0.33 -0.2
473,225 + Rv0393 0.33 +0.2
473,225 + Rv0393 0.33 -1.3
473,225 + Rv0393 0.33 -0.3
473,226 - Rv0393 0.34 -0.2

Or see this region's nucleotide sequence