Experiment: 7H9 with Levofloxacin 0.3 ug/mL
Only strains with sufficient reads to estimate fitness are shown,
but the strain fitness values are still rather noisy and may be biased towards zero.
Strains near the edge of a gene are not shown as being associated with that
gene (they are in grey).
Strains in the central 10-90% of a gene are color coded by the insertion's strand.
Usually, "+" means that the selectable marker is encoded on the forward strand,
i.e., transcribed rightward.
500 nt Rv0373c and Rv0374c overlap by 4 nucleotides Rv0374c and Rv0375c are separated by 14 nucleotides Rv0375c and Rv0376c are separated by 75 nucleotides
Rv0373c: Rv0373c - Probable carbon monoxyde dehydrogenase (large chain), at 449,404 to 451,803
Rv0373c
Rv0374c: Rv0374c - Probable carbon monoxyde dehydrogenase (small chain), at 451,800 to 452,279
Rv0374c
Rv0375c: Rv0375c - Probable carbon monoxyde dehydrogenase (medium chain), at 452,294 to 453,154
Rv0375c
Rv0376c: Rv0376c - Conserved hypothetical protein, at 453,230 to 454,372
Rv0376c
Position (kb) 452
453
454 Strain fitness (log2 ratio) -3
-2
-1
0
1 at 451.492 kb on + strand, within Rv0373c at 451.492 kb on + strand, within Rv0373c at 451.864 kb on + strand, within Rv0374c at 451.955 kb on + strand, within Rv0374c at 452.386 kb on - strand, within Rv0375c at 452.386 kb on - strand, within Rv0375c at 453.007 kb on - strand, within Rv0375c at 453.189 kb on - strand at 453.189 kb on - strand at 453.242 kb on + strand at 453.243 kb on - strand at 453.243 kb on - strand at 453.243 kb on - strand at 453.243 kb on - strand at 453.243 kb on - strand at 453.246 kb on + strand at 453.505 kb on - strand, within Rv0376c at 454.137 kb on - strand, within Rv0376c
Per-strain Table
Position Strand Gene LocusTag Fraction 7H9 with Levofloxacin 0.3 ug/mL remove 451,492 + Rv0373c 0.87 +0.9 451,492 + Rv0373c 0.87 -1.0 451,864 + Rv0374c 0.13 +1.4 451,955 + Rv0374c 0.32 -0.3 452,386 - Rv0375c 0.11 -2.3 452,386 - Rv0375c 0.11 -1.9 453,007 - Rv0375c 0.83 -1.7 453,189 - -0.8 453,189 - +1.1 453,242 + -0.6 453,243 - -0.3 453,243 - +0.5 453,243 - -1.5 453,243 - -3.1 453,243 - -1.1 453,246 + -1.4 453,505 - Rv0376c 0.24 -0.9 454,137 - Rv0376c 0.79 -0.6
Or see this region's nucleotide sequence