Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv0362

Experiment: 7H9 with Levofloxacin 0.3 ug/mL

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv0361 and Rv0362 are separated by 221 nucleotidesRv0362 and Rv0363c are separated by 11 nucleotides Rv0361: Rv0361 - Probable conserved membrane protein, at 438,822 to 439,649 Rv0361 Rv0362: Rv0362 - Possible Mg2+ transport transmembrane protein MgtE, at 439,871 to 441,253 Rv0362 Rv0363c: Rv0363c - Probable fructose-bisphosphate aldolase Fba, at 441,265 to 442,299 Rv0363c Position (kb) 439 440 441 442Strain fitness (log2 ratio) -2 -1 0 1 2 3at 439.423 kb on - strand, within Rv0361at 439.423 kb on - strand, within Rv0361at 439.432 kb on - strand, within Rv0361at 439.696 kb on + strandat 439.696 kb on + strandat 439.799 kb on + strandat 439.800 kb on - strandat 439.833 kb on - strandat 440.064 kb on + strand, within Rv0362at 440.064 kb on + strand, within Rv0362at 440.065 kb on - strand, within Rv0362at 440.396 kb on + strand, within Rv0362at 440.397 kb on - strand, within Rv0362at 440.402 kb on + strand, within Rv0362at 440.402 kb on + strand, within Rv0362at 440.402 kb on + strand, within Rv0362at 440.605 kb on - strand, within Rv0362at 440.705 kb on + strand, within Rv0362at 440.706 kb on - strand, within Rv0362at 440.730 kb on + strand, within Rv0362at 440.996 kb on - strand, within Rv0362at 441.206 kb on + strandat 441.206 kb on + strand

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Levofloxacin 0.3 ug/mL
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439,423 - Rv0361 0.73 -1.6
439,423 - Rv0361 0.73 -0.6
439,432 - Rv0361 0.74 +1.0
439,696 + -0.8
439,696 + +0.5
439,799 + +3.6
439,800 - +1.0
439,833 - -0.7
440,064 + Rv0362 0.14 -0.7
440,064 + Rv0362 0.14 +0.0
440,065 - Rv0362 0.14 +0.2
440,396 + Rv0362 0.38 -0.2
440,397 - Rv0362 0.38 -0.1
440,402 + Rv0362 0.38 +0.3
440,402 + Rv0362 0.38 +0.7
440,402 + Rv0362 0.38 +0.4
440,605 - Rv0362 0.53 -0.2
440,705 + Rv0362 0.60 -2.1
440,706 - Rv0362 0.60 -0.6
440,730 + Rv0362 0.62 -0.1
440,996 - Rv0362 0.81 -0.4
441,206 + +0.3
441,206 + +0.4

Or see this region's nucleotide sequence