Experiment: 7H9 with Levofloxacin 0.3 ug/mL
Only strains with sufficient reads to estimate fitness are shown,
but the strain fitness values are still rather noisy and may be biased towards zero.
Strains near the edge of a gene are not shown as being associated with that
gene (they are in grey).
Strains in the central 10-90% of a gene are color coded by the insertion's strand.
Usually, "+" means that the selectable marker is encoded on the forward strand,
i.e., transcribed rightward.
500 nt Rv0297 and Rv0298 are separated by 142 nucleotides Rv0298 and Rv0299 overlap by 4 nucleotides Rv0299 and Rv0300 are separated by 47 nucleotides Rv0300 and Rv0301 overlap by 4 nucleotides Rv0301 and Rv0302 are separated by 135 nucleotides
Rv0297: Rv0297 - PE-PGRS family protein PE_PGRS5, at 361,334 to 363,109
Rv0297
Rv0298: Rv0298 - Hypothetical protein, at 363,252 to 363,479
Rv0298
Rv0299: Rv0299 - Hypothetical protein, at 363,476 to 363,778
Rv0299
Rv0300: Rv0300 - Possible antitoxin VapB2, at 363,826 to 364,047
Rv0300
Rv0301: Rv0301 - Possible toxin VapC2, at 364,044 to 364,469
Rv0301
Rv0302: Rv0302 - Probable transcriptional regulatory protein (probably TetR/AcrR-family), at 364,605 to 365,237
Rv0302
Position (kb) 363
364
365 Strain fitness (log2 ratio) -2
-1
0
1
2 at 362.936 kb on - strand at 363.130 kb on + strand at 363.130 kb on + strand at 363.131 kb on - strand at 363.134 kb on + strand at 363.135 kb on - strand at 363.135 kb on - strand at 363.135 kb on - strand at 363.135 kb on - strand at 363.169 kb on + strand at 363.169 kb on + strand at 363.230 kb on + strand at 363.230 kb on + strand at 363.231 kb on - strand at 363.231 kb on - strand at 363.236 kb on + strand at 363.240 kb on - strand at 363.396 kb on + strand, within Rv0298 at 363.404 kb on + strand, within Rv0298 at 363.436 kb on - strand, within Rv0298 at 363.450 kb on + strand, within Rv0298 at 363.527 kb on + strand, within Rv0299 at 363.814 kb on + strand at 363.815 kb on - strand at 363.836 kb on + strand at 363.837 kb on - strand at 363.837 kb on - strand at 363.866 kb on + strand, within Rv0300 at 363.866 kb on + strand, within Rv0300 at 363.867 kb on - strand, within Rv0300 at 364.027 kb on - strand at 364.144 kb on + strand, within Rv0301 at 364.145 kb on - strand, within Rv0301 at 364.145 kb on - strand, within Rv0301 at 364.145 kb on - strand, within Rv0301 at 364.174 kb on + strand, within Rv0301 at 364.175 kb on - strand, within Rv0301 at 364.175 kb on - strand, within Rv0301 at 364.251 kb on + strand, within Rv0301 at 364.251 kb on + strand, within Rv0301 at 364.252 kb on - strand, within Rv0301 at 364.252 kb on - strand, within Rv0301 at 364.252 kb on - strand, within Rv0301 at 364.256 kb on - strand, within Rv0301 at 364.256 kb on - strand, within Rv0301 at 364.256 kb on - strand, within Rv0301 at 364.381 kb on + strand, within Rv0301 at 364.382 kb on - strand, within Rv0301 at 364.382 kb on - strand, within Rv0301 at 364.568 kb on - strand at 364.741 kb on + strand, within Rv0302 at 364.755 kb on - strand, within Rv0302 at 364.755 kb on - strand, within Rv0302 at 364.758 kb on + strand, within Rv0302 at 364.942 kb on - strand, within Rv0302
Per-strain Table
Position Strand Gene LocusTag Fraction 7H9 with Levofloxacin 0.3 ug/mL remove 362,936 - -2.5 363,130 + -0.6 363,130 + -0.3 363,131 - -0.9 363,134 + +0.2 363,135 - -0.8 363,135 - +1.0 363,135 - -1.1 363,135 - -0.7 363,169 + -0.3 363,169 + -0.5 363,230 + -0.1 363,230 + -0.6 363,231 - -0.2 363,231 - -0.2 363,236 + -0.6 363,240 - -0.6 363,396 + Rv0298 0.63 -0.4 363,404 + Rv0298 0.67 -0.2 363,436 - Rv0298 0.81 +0.4 363,450 + Rv0298 0.87 -0.7 363,527 + Rv0299 0.17 -0.6 363,814 + +0.3 363,815 - +0.4 363,836 + -1.1 363,837 - +0.2 363,837 - -1.0 363,866 + Rv0300 0.18 +2.0 363,866 + Rv0300 0.18 +0.7 363,867 - Rv0300 0.18 +0.0 364,027 - +0.6 364,144 + Rv0301 0.23 -0.4 364,145 - Rv0301 0.24 -0.3 364,145 - Rv0301 0.24 -0.6 364,145 - Rv0301 0.24 -1.2 364,174 + Rv0301 0.31 -0.1 364,175 - Rv0301 0.31 -0.0 364,175 - Rv0301 0.31 -0.1 364,251 + Rv0301 0.49 -0.9 364,251 + Rv0301 0.49 -1.9 364,252 - Rv0301 0.49 -0.6 364,252 - Rv0301 0.49 -0.6 364,252 - Rv0301 0.49 +0.2 364,256 - Rv0301 0.50 +0.1 364,256 - Rv0301 0.50 -2.4 364,256 - Rv0301 0.50 -1.6 364,381 + Rv0301 0.79 +0.5 364,382 - Rv0301 0.79 -0.5 364,382 - Rv0301 0.79 -2.1 364,568 - -0.7 364,741 + Rv0302 0.21 +0.6 364,755 - Rv0302 0.24 -1.9 364,755 - Rv0302 0.24 -0.1 364,758 + Rv0302 0.24 -0.6 364,942 - Rv0302 0.53 -1.6
Or see this region's nucleotide sequence